M
Martha E. Shenton
Researcher at Brigham and Women's Hospital
Publications - 626
Citations - 48184
Martha E. Shenton is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Schizophrenia & Fractional anisotropy. The author has an hindex of 106, co-authored 586 publications receiving 44244 citations. Previous affiliations of Martha E. Shenton include Cambridge Health Alliance & Beth Israel Deaconess Medical Center.
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Journal ArticleDOI
A review of MRI findings in schizophrenia
TL;DR: The 193 peer reviewed MRI studies reported in the current review span the period from 1988 to August, 2000 and have led to more definitive findings of brain abnormalities in schizophrenia than any other time period in the history of schizophrenia research.
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Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma
Mark W. Gilbertson,Martha E. Shenton,Martha E. Shenton,Martha E. Shenton,Aleksandra A. Ciszewski,Kiyoto Kasai,Natasha B. Lasko,Natasha B. Lasko,Scott P. Orr,Scott P. Orr,Roger K. Pitman +10 more
TL;DR: In monozygotic twins discordant for trauma exposure, it is found evidence that smaller hippocampi indeed constitute a risk factor for the development of stress-related psychopathology.
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Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia
Susan Whitfield-Gabrieli,Heidi W. Thermenos,Snezana Milanovic,Ming T. Tsuang,Stephen V. Faraone,Robert W. McCarley,Martha E. Shenton,Alan I. Green,Alfonso Nieto-Castanon,Peter S. LaViolette,Joanne Wojcik,John D. E. Gabrieli,Larry J. Seidman +12 more
TL;DR: Among patients, the magnitude of MPFC task suppression negatively correlated with default connectivity, suggesting an association between the hyperactivation and hyperconnectivity in schizophrenia.
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Abnormalities of the left temporal lobe and thought disorder in schizophrenia. A quantitative magnetic resonance imaging study.
Martha E. Shenton,Ron Kikinis,Ferenc A. Jolesz,Seth D. Pollak,Marjorie LeMay,Cynthia G. Wible,Hiroto Hokama,John D. Martin,Dave Metcalf,Michael J. Coleman,Robert W. McCarley +10 more
TL;DR: New MRI neuroimaging techniques are used to derive volume measurements and three-dimensional reconstructions of temporal-lobe structures in vivo in 15 right-handed men with chronic schizophrenia and 15 matched controls to discover the degree of thought disorder is related to the size of the reduction in volume of the left posterior superior temporal gyrus.
Journal ArticleDOI
Magnetic resonance imaging study of hippocampal volume in chronic, combat-related posttraumatic stress disorder.
Tamara V. Gurvits,Martha E. Shenton,Martha E. Shenton,Hiroto Hokama,Hiroto Hokama,Hirokazu Ohta,Hirokazu Ohta,Natasha B. Lasko,Natasha B. Lasko,Mark W. Gilbertson,Mark W. Gilbertson,Scott P. Orr,Scott P. Orr,Ron Kikinis,Ron Kikinis,Ferenc A. Jolesz,Ferenc A. Jolesz,Robert W. McCarley,Robert W. McCarley,Roger K. Pitman,Roger K. Pitman +20 more
TL;DR: Hippocampal volume was directly correlated with combat exposure, which suggests that traumatic stress may damage the hippocampus and smaller hippocampi volume may be a pre-existing risk factor for combat exposure and/or the development of PTSD upon combat exposure.