M
Martin Distel
Researcher at University of California, San Diego
Publications - 69
Citations - 2730
Martin Distel is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Zebrafish & Medicine. The author has an hindex of 19, co-authored 47 publications receiving 2283 citations. Previous affiliations of Martin Distel include Braunschweig University of Technology & Technische Universität München.
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Journal ArticleDOI
Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivo
Daniel Razansky,Martin Distel,Claudio Vinegoni,Rui Ma,Norbert Perrimon,Reinhard W. Köster,Vasilis Ntziachristos +6 more
TL;DR: By performing whole-body imaging of two biologically important and optically diffuse model organisms, Drosophila melanogaster pupae and adult zebrafish, the facility to resolve tissue-specific expression of eGFP and mCherrry fluorescent proteins for precise morphological and functional observations in vivo is demonstrated.
Journal ArticleDOI
Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity
Jin Li,Tamara Casteels,Thomas Frogne,Camilla Ingvorsen,Christian Honoré,Monica Courtney,Kilian Huber,Nicole Schmitner,Robin A. Kimmel,Roman A. Romanov,Roman A. Romanov,Caterina Sturtzel,Charles-Hugues Lardeau,Johanna Klughammer,Matthias Farlik,Sara Sdelci,Andhira Vieira,Fabio Avolio,François Briand,Igor Baburin,Peter Májek,Florian M. Pauler,Thomas Penz,Alexey Stukalov,Manuela Gridling,Katja Parapatics,Charlotte Barbieux,Ekaterine Berishvili,Ekaterine Berishvili,Andreas Spittler,Jacques Colinge,Keiryn L. Bennett,Steffen Hering,Thierry Sulpice,Christoph Bock,Christoph Bock,Christoph Bock,Martin Distel,Tibor Harkany,Tibor Harkany,Dirk Meyer,Giulio Superti-Furga,Giulio Superti-Furga,Patrick Collombat,Jacob Hecksher-Sørensen,Stefan Kubicek +45 more
TL;DR: It is shown that the protein gephyrin is the mammalian target of these antimalarial drugs and that the mechanism of action of these molecules depends on the enhancement of GABAA receptor signaling.
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Optimized Gal4 genetics for permanent gene expression mapping in zebrafish
TL;DR: A systematic optimization of zebrafish Gal4-UAS genetics is reported by establishing an optimized KalTA4-activator (KalTA4), which demonstrates prolonged and maintained expression by Kalooping, a technique that can be used for permanent spatiotemporal genetic fate mapping and targeted transgene expression in zebra fish.
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A zebrafish model of tauopathy allows in vivo imaging of neuronal cell death and drug evaluation
Dominik Paquet,Ratan Bhat,Astrid Sydow,Eva-Maria Mandelkow,Stefan von Berg,Sven Hellberg,Johanna Fälting,Martin Distel,Reinhard W. Köster,Bettina Schmid,Christian Haass +10 more
TL;DR: This transgenic zebrafish model may become a valuable tool for further studies of the neuropathology of dementia and be used to identify compounds targeting the TAU kinase glycogen synthase kinase 3beta (GSK3beta).
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Kita driven expression of oncogenic HRAS leads to early onset and highly penetrant melanoma in zebrafish.
Cristina Santoriello,Elisa Gennaro,Viviana Anelli,Martin Distel,Amanda Kelly,Reinhard W. Köster,Adam Hurlstone,Marina Mione +7 more
TL;DR: In this article, the Gal4-UAS system was used to develop a zebrafish transgenic line that expressed oncogenic HRAS under the kita promoter for melanoma detection.