M
Martin Pelletier
Researcher at Laval University
Publications - 68
Citations - 4409
Martin Pelletier is an academic researcher from Laval University. The author has contributed to research in topics: Cytokine & Proinflammatory cytokine. The author has an hindex of 28, co-authored 64 publications receiving 3469 citations. Previous affiliations of Martin Pelletier include University of Verona & Institut national de la recherche scientifique.
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Glucuronidated Metabolites of Bisphenols A and S Alter the Properties of Normal Urothelial and Bladder Cancer Cells
Ève Pellerin,Félix-Antoine Pellerin,Stéphane Chabaud,F. Pouliot,Martin Pelletier,Stéphane Bolduc +5 more
TL;DR: Exposure to glucuronidated BPA or BPS decreased the bioenergetics and activity of normal urothelial cells, while increasing these parameters for bladder cancer cells, suggesting that BP metabolites are not as inactive as initially believed, and their ubiquitous presence in the urine could promote bladder cancer progression.
Journal ArticleDOI
Peripheral Neuroprotective and Immunomodulatory Effects of 5α-Reductase Inhibitors in Parkinson’s Disease Models
Andrée Poirier,Mélissa Côté,Hend Jarras,Nadhir Litim,Jérôme Lamontagne-Proulx,Sara Al-Sweidi,Marc Morissette,Asmaa Lachhab,Martin Pelletier,Thérèse Di Paolo,Denis Soulet +10 more
TL;DR: Results indicate that dutasteride treatment prevents enteric neuronal damages in the MPTP mouse model, at least in part through anti-inflammatory and mitochondrial effects, suggesting that drug repurposing of dutasterside might be a promising avenue to treat enteric neuroinflammation in early PD.
Journal ArticleDOI
Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic-mitochondrial tricarboxylic acid cycle that can be targeted for therapeutic purposes in prostate cancer.
Kevin Gonthier,Cindy Weidmann,Line Berthiaume,Cynthia Jobin,Aurélie Lacouture,Camille Lafront,Mario Harvey,Bertrand Neveu,Jeremy Loehr,Alain Bergeron,Yves Fradet,Louis Lacombe,J. Riopel,Eva Latulippe,Chantal Atallah,Michael Shum,Jean Philippe Lambert,F. Pouliot,Martin Pelletier,Étienne Audet-Walsh +19 more
TL;DR: In this article , the androgen receptor (AR) is an established orchestrator of cell metabolism in prostate cancer (PCa), notably by inducing an oxidative mitochondrial program, but not its mitochondrial counterparts IDH2 and IDH3.