M
Mary E. Wlodek
Researcher at University of Melbourne
Publications - 202
Citations - 4893
Mary E. Wlodek is an academic researcher from University of Melbourne. The author has contributed to research in topics: Offspring & Pregnancy. The author has an hindex of 35, co-authored 189 publications receiving 4251 citations. Previous affiliations of Mary E. Wlodek include University of Western Australia & St. Vincent's Institute of Medical Research.
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Journal ArticleDOI
Adolescence and the next generation
George C Patton,George C Patton,Craig A. Olsson,Vegard Skirbekk,Vegard Skirbekk,Richard Saffery,Mary E. Wlodek,Peter Azzopardi,Marcin Stonawski,Bruce Rasmussen,Elizabeth Spry,Elizabeth Spry,Kate L Francis,Zulfiqar A Bhutta,Nicholas J Kassebaum,Nicholas J Kassebaum,Ali H. Mokdad,Christopher J L Murray,Andrew M. Prentice,Nicola J. Reavley,Peter Sheehan,Kim Sweeny,Russell M Viner,Susan M Sawyer,Susan M Sawyer +24 more
TL;DR: Investing in today’s adolescents, the largest cohort in human history, will yield great dividends for future generations through distinct processes in males and females.
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Normal Lactational Environment Restores Nephron Endowment and Prevents Hypertension after Placental Restriction in the Rat
TL;DR: It is shown for the first time that a prenatally induced nephron deficit can be restored by correcting growth restriction during lactation and the prenatal and postnatal nutritional environments in the programming of adult hypertension, associated with distinct renal changes are identified.
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Growth restriction before or after birth reduces nephron number and increases blood pressure in male rats
TL;DR: It is suggested that restriction of both perinatal and early postnatal growth increase blood pressure in male offspring and that the earlyPostnatal period is a critical time for nephron endowment in the rat.
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Uteroplacental insufficiency causes a nephron deficit, modest renal insufficiency but no hypertension with ageing in female rats
Karen M. Moritz,Marc Q. Mazzuca,Andrew L. Siebel,A. L. Mibus,D. Arena,Marianne Tare,Julie A. Owens,Mary E. Wlodek +7 more
TL;DR: Growth, blood pressure and nephron endowment in female offspring from mothers which underwent bilateral uterine vessel ligation on day 18 of pregnancy were examined, suggesting that perinatally growth restricted female offspring may be susceptible to onset of renal injury and renal insufficiency with ageing in the absence of concomitant hypertension.
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Changes in pituitary responses to synthetic ovine corticotrophin releasing factor in fetal sheep.
TL;DR: There was a significant effect of time on basal ACTH concentrations with a mean increase of approximately 5 pg ACTH per millilitre of plasma per 5-day sampling interval, and plasma cortisol concentrations were elevated following 1- and 10-micrograms injections of oCRF.