M
Mary Porteous
Researcher at Western General Hospital
Publications - 145
Citations - 15885
Mary Porteous is an academic researcher from Western General Hospital. The author has contributed to research in topics: Population & Breast cancer. The author has an hindex of 53, co-authored 142 publications receiving 14180 citations. Previous affiliations of Mary Porteous include University of Edinburgh.
Papers
More filters
Journal ArticleDOI
Mutations in the activin receptor–like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2
Darren W. Johnson,Jonathan Berg,Jonathan Berg,Melanie A. Baldwin,Carol J. Gallione,Ivonne Marondel,S.-J. Yoon,Timothy T. Stenzel,Marcy C. Speer,Margaret A. Pericak-Vance,Austin G. Diamond,Alan E. Guttmacher,Charles E. Jackson,L. Attisano,Raju Kucherlapati,Mary Porteous,Douglas A. Marchuk +16 more
TL;DR: A new 4 cM interval for ORW2 is reported that does not overlap with any previously defined and suggests a critical role for ALK1 in the control of blood vessel development or repair.
Journal ArticleDOI
International guidelines for the diagnosis and management of hereditary haemorrhagic telangiectasia
Marie E. Faughnan,Valerie A. Palda,Guadalupe Garcia-Tsao,Urban W. Geisthoff,Jamie McDonald,Deborah D. Proctor,J Spears,Dale H. Brown,Elisabetta Buscarini,Mark S. Chesnutt,Vincent Cottin,Arupa Ganguly,James R. Gossage,Alan E. Guttmacher,Robert H. Hyland,Shelley J. Kennedy,Joshua R. Korzenik,J J Mager,A P Ozanne,Jay F. Piccirillo,Daniel Picus,Henri Plauchu,Mary Porteous,Reed E. Pyeritz,Douglas A. Ross,Carlo Sabbà,Karen L. Swanson,Peter B. Terry,M C Wallace,C.J.J. Westermann,Robert I. White,Lawrence H. Young,Roberto Zarrabeitia +32 more
TL;DR: The goal of this international HHT guidelines process was to develop evidence-informed consensus guidelines regarding the diagnosis of HHT and the prevention of H HT-related complications and treatment of symptomatic disease.
Journal ArticleDOI
Integrated care pathways
TL;DR: The degree to which integrated care pathways succeed in realising their potential for improving patient care is still uncertain, but enough evidence exists in their favour to justify more widespread evaluation of their impact.
Journal ArticleDOI
Cancer Risks for BRCA1 and BRCA2 Mutation Carriers: Results From Prospective Analysis of EMBRACE
Nasim Mavaddat,Susan Peock,Debra Frost,Steve Ellis,Radka Platte,Elena Fineberg,D. Gareth Evans,Louise Izatt,Rosalind A. Eeles,Julian Adlard,Rosemarie Davidson,Diana Eccles,Trevor Cole,Jackie Cook,Carole Brewer,Marc Tischkowitz,Fiona Douglas,Shirley Hodgson,Lisa Walker,Mary Porteous,Patrick J. Morrison,Lucy Side,M. John Kennedy,C. E. Houghton,Alan Donaldson,Mark T. Rogers,Huw Dorkins,Zosia Miedzybrodzka,Helen Gregory,Jacqueline Eason,Julian Barwell,Emma McCann,Alex Murray,Antonis C. Antoniou,Douglas F. Easton +34 more
TL;DR: Prospective risk estimates for breast cancer, ovarian cancer, and contralateral breast cancer in a prospective series of mutation carriers confirm findings from retrospective studies that common breast cancer susceptibility alleles in combination are predictive of breast cancer risk for BRCA2 carriers.
Journal ArticleDOI
Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24
Brent W. Zanke,Celia M. T. Greenwood,Celia M. T. Greenwood,Jagadish Rangrej,Rafal Kustra,Rafal Kustra,Albert Tenesa,Susan M. Farrington,James G. D. Prendergast,Sylviane Olschwang,Theodore Chiang,Edgar Crowdy,Vincent Ferretti,Philippe Laflamme,Saravanan Sundararajan,Stéphanie Roumy,Jean François Olivier,Frederick Robidoux,Robert Sladek,Alexandre Montpetit,Peter T. Campbell,Stéphane Bézieau,Anne Marie O'Shea,George Zogopoulos,Michelle Cotterchio,Michelle Cotterchio,Polly A. Newcomb,John R. McLaughlin,John R. McLaughlin,Ban Younghusband,Roger C. Green,Jane Green,Mary Porteous,Harry Campbell,Hélène Blanché,Mourad Sahbatou,Emmanuel Tubacher,Catherine Bonaïti-Pellié,Bruno Buecher,Elio Riboli,Sébastien Küry,Stephen J. Chanock,John D. Potter,Gilles Thomas,Steven Gallinger,Steven Gallinger,Thomas J. Hudson,Thomas J. Hudson,Malcolm G. Dunlop +48 more
TL;DR: Using a multistage genetic association approach comprising 7,480 affected individuals and 7,779 controls, markers in chromosomal region 8q24 associated with colorectal cancer were identified and this locus has been implicated in prostate cancer.