M
Masato Inazu
Researcher at Tokyo Medical University
Publications - 70
Citations - 1843
Masato Inazu is an academic researcher from Tokyo Medical University. The author has contributed to research in topics: Choline & Choline transporter. The author has an hindex of 24, co-authored 66 publications receiving 1599 citations.
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Rosmarinic acid and caffeic acid produce antidepressive-like effect in the forced swimming test in mice.
TL;DR: The results suggest that both caffeic acid and rosmarinic acid may produce antidepressive-like activity via some mechanism(s) other than the inhibition of monoamine transporters and monoamine oxidase.
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Expression and functional characterization of the extraneuronal monoamine transporter in normal human astrocytes
TL;DR: The results showed that the EMT is functionally expressed in NHA and may also play a key role in the disposition of cationic drugs, neurosteroids, the neurotoxin MPP+ and monoamine neurotransmitters in the brain.
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Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells
Shota Moriya,Xiao-Fang Che,Seiichiro Komatsu,Akihisa Abe,Tomohiro Kawaguchi,Akihiko Gotoh,Masato Inazu,Akio Tomoda,Keisuke Miyazawa +8 more
TL;DR: Simultaneously targeting two major intracellular protein degradation systems such as the ubiquitin-proteasome system by BZ and the autophagy-lysosomes system by a macrolide antibiotic enhances ER stress-mediated apoptosis in MM cells.
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Astroglial dopamine transport is mediated by norepinephrine transporter.
TL;DR: It is suggested that cortical astrocytes regulate extracellular DA and NE concentrations through the uptake ofDA and NE by the glial NET but not by DAT, and an uptake2 mechanism contributes to DA uptake in cortical astROcytes.
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Pharmacological characterization and visualization of the glial serotonin transporter.
Masato Inazu,Hiroshi Takeda,Hideaki Ikoshi,Masaya Sugisawa,Yoshihiro Uchida,Teruhiko Matsumiya +5 more
TL;DR: The pharmacological experiments indicate that this uptake process takes place through glial SERT that is very similar to neuronal SERT, and the present data indicate that the presence of the mRNA and protein for the neuronal Sert were established in cultured rat astrocytes, andThe polypeptide portion of SERT in astroCytes and frontal cortex could be the same gene product.