Journal ArticleDOI
Rosmarinic acid and caffeic acid produce antidepressive-like effect in the forced swimming test in mice.
Reads0
Chats0
TLDR
The results suggest that both caffeic acid and rosmarinic acid may produce antidepressive-like activity via some mechanism(s) other than the inhibition of monoamine transporters and monoamine oxidase.About:
This article is published in European Journal of Pharmacology.The article was published on 2002-08-09. It has received 191 citations till now. The article focuses on the topics: Rosmarinic acid & Caffeic acid.read more
Citations
More filters
Journal ArticleDOI
Bioactivity and analysis of biophenols recovered from olive mill waste.
Hassan K. Obied,Malcolm S. Allen,Danny R. Bedgood,Paul D. Prenzler,Kevin Robards,Regine Stockmann +5 more
TL;DR: The phenolic profile of OMW is complex, yet this complexity has not been fully exploited in the valorization of the waste, and most work on the bioactivity of O MW has focused on antioxidant and antimicrobial activities.
Journal ArticleDOI
Therapeutic effects of herbal extracts and constituents in animal models of psychiatric disorders.
TL;DR: Herbal remedies that have demonstrable psychotherapeutic activities have provided a potential to psychiatric pharmaceuticals and deserve increased attention in future studies.
Journal ArticleDOI
Chlorogenic acids and related compounds in medicinal plants and infusions
Viviane X. Marques,Adriana Farah +1 more
TL;DR: In this paper, the chlorogenic acid (CGA) composition of 14 dried medicinal plants was determined by HPLC-UV and LC-DAD-ESI-MS, and the plants with the highest CGA contents were Ilex paraguariensis, Bacharis genistelloides, Pimpinella anisum, Achyrochine satureioides, Camellia sinensis, Melissa officinalis and Cymbopogon citratus, with 84.7 µg/100 µg, dry weight.
Journal ArticleDOI
Melissa officinalis L. - A review of its traditional uses, phytochemistry and pharmacology
TL;DR: The data reviewed here revealed that M. officinalis is a potential source for the treatment of a wide range of diseases especially anxiety and some other CNS disorders, though confirmatory trials are warranted to substantiate these effects in the clinical setting.
Journal ArticleDOI
A natural scavenger of peroxynitrites, rosmarinic acid, protects against impairment of memory induced by Aβ25–35
TL;DR: It is demonstrated that the memory protective effects of RA in the neurotoxicity of Abeta(25-35) is due to its scavenging of ONOO(-), and that daily consumption of RA may protect against memory impairments observed in AD.
References
More filters
Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Depression: a new animal model sensitive to antidepressant treatments
R D Porsolt,M Le Pichon,M Jalfre +2 more
TL;DR: Results presented below indicate that immobility is reduced by different treatments known to be therapeutic in depression including three drugs, iprindole, mianserin and viloxazine which although clinically active show little or no ‘antidepressant’ activity in the usual animal tests.
Journal ArticleDOI
The catecholamine hypothesis of affective disorders: a review of supporting evidence
TL;DR: The "catecholamine hypothesis of affective disorders" as discussed by the authors suggests that depression is associated with an absolute or relative decrease in catecholamines, particularly norepinephrine, available at central adrenergic receptor sites.
Journal ArticleDOI
Norepinephrine in Depressive Reactions: A Review
William E. Bunney,John M. Davis +1 more
TL;DR: Rosenblatt et al, 9 in 1959, were among the first to specifically suggest that changes in brain norepinephrine (NEP) may be involved in depression, and hypothesized that the depressive state might be associated with a relative decrease of nore Alpinephrine.
Journal ArticleDOI
“Behavioural despair” in rats and mice: Strain differences and the effects of imipramine
TL;DR: Important differences exist between strains in both the amount of immobility observed and the effects of imipramine, and strain differences should be taken into account in attempts to replicate results from one laboratory to another.