M
Mathieu F. Bakhoum
Researcher at University of California, San Diego
Publications - 33
Citations - 697
Mathieu F. Bakhoum is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 8, co-authored 28 publications receiving 288 citations. Previous affiliations of Mathieu F. Bakhoum include Columbia University Medical Center & University of Texas Medical Branch.
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Journal ArticleDOI
A molecular single-cell lung atlas of lethal COVID-19.
Johannes C. Melms,Jana Biermann,Huachao Huang,Yiping Wang,Ajay Nair,Somnath Tagore,Igor Katsyv,André F. Rendeiro,Amit Dipak Amin,Denis Schapiro,Denis Schapiro,Chris J. Frangieh,Chris J. Frangieh,Adrienne M. Luoma,Aveline Filliol,Yinshan Fang,Hiranmayi Ravichandran,Mariano G. Clausi,George A. Alba,Meri Rogava,Sean W. Chen,Patricia Ho,Daniel T. Montoro,Daniel T. Montoro,Adam E. Kornberg,Arnold Han,Mathieu F. Bakhoum,Niroshana Anandasabapathy,Mayte Suárez-Fariñas,Samuel F. Bakhoum,Yaron Bram,Alain C. Borczuk,Xinzheng V. Guo,Jay H. Lefkowitch,Charles C. Marboe,Stephen M. Lagana,Armando Del Portillo,Emily J. Tsai,Emmanuel Zorn,Glen S. Markowitz,Robert F. Schwabe,Robert E. Schwartz,Olivier Elemento,Anjali Saqi,Hanina Hibshoosh,Jianwen Que,Benjamin Izar +46 more
TL;DR: In this paper, the authors performed single-nucleus RNA sequencing of about 116,000 nuclei from the lungs of nineteen individuals who died of COVID-19 and underwent rapid autopsy and seven control individuals.
Journal ArticleDOI
Paracentral Acute Middle Maculopathy and the Ischemic Cascade Associated With Retinal Vascular Occlusion.
Mathieu F. Bakhoum,K. Bailey Freund,Rosa Dolz-Marco,Belinda C S Leong,Caroline R. Baumal,Jay S. Duker,David Sarraf +6 more
TL;DR: OCT findings suggestive of an ischemic cascade in eyes with retinal vascular occlusion are described, suggesting the middle retina at the level of the deep capillary plexus, especially at the venular pole, may be more vulnerable to isChemic injury.
Journal ArticleDOI
TDP-43 Phosphorylation by casein kinase Iε promotes oligomerization and enhances toxicity in vivo
Darshana K. Choksi,Bidisha Roy,Shreyasi Chatterjee,Tanzeen Yusuff,Mathieu F. Bakhoum,Urmi Sengupta,Surendra S. Ambegaokar,Rakez Kayed,George R. Jackson +8 more
TL;DR: It is demonstrated that human TDP-43(Q331K) undergoes cytoplasmic localization and aggregates when misexpressed in Drosophila when compared with wild-type and M337V forms, and CKIε is identified as a potent TPD-43 kinase in vivo and implicate oligomeric species as the toxic entities in T DP-43 proteinopathies.
Journal ArticleDOI
Molecular Characteristics of Uveal Melanoma: Insights from the Cancer Genome Atlas (TCGA) Project.
Mathieu F. Bakhoum,Bita Esmaeli +1 more
TL;DR: The Cancer Genome Atlas (TCGA) uveal melanoma project was a comprehensive multi-platform deep molecular investigation that identified four different clusters (subgroups) of patients paralleling prognosis in addition to identification of important mutations for the first time.
Journal ArticleDOI
Ocular adnexal lymphoma: validation of American Joint Committee on Cancer seventh edition staging guidelines
Matthew C. Sniegowski,Dianna B. Roberts,Mathieu F. Bakhoum,Peter Mc Laughlin,Vivian T. Yin,Francesco Turturro,Bita Esmaeli +6 more
TL;DR: AJCC seventh edition T category was predictive of DFS in patients with OAL and more advanced Ann Arbor stage was associated with decreased 5-year DFS; however, this trend was not statistically significant.