H
Hiranmayi Ravichandran
Researcher at Cornell University
Publications - 20
Citations - 1801
Hiranmayi Ravichandran is an academic researcher from Cornell University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 7, co-authored 11 publications receiving 923 citations. Previous affiliations of Hiranmayi Ravichandran include Harvard University.
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Journal ArticleDOI
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
Andrew S. Venteicher,Andrew S. Venteicher,Itay Tirosh,Christine Hebert,Christine Hebert,Keren Yizhak,Keren Yizhak,Cyril Neftel,Cyril Neftel,Cyril Neftel,Mariella G. Filbin,Mariella G. Filbin,Volker Hovestadt,Volker Hovestadt,Leah E. Escalante,Leah E. Escalante,McKenzie Shaw,McKenzie Shaw,Christopher Rodman,Shawn M. Gillespie,Danielle Dionne,Christina C. Luo,Hiranmayi Ravichandran,Ravindra Mylvaganam,Christopher Mount,Maristela L. Onozato,Brian V. Nahed,Hiroaki Wakimoto,William T. Curry,A. John Iafrate,Miguel Rivera,Miguel Rivera,Matthew P. Frosch,Todd R. Golub,Todd R. Golub,Todd R. Golub,Priscilla K. Brastianos,Gad Getz,Gad Getz,Anoop P. Patel,Michelle Monje,Daniel P. Cahill,Orit Rozenblatt-Rosen,David N. Louis,Bradley E. Bernstein,Bradley E. Bernstein,Aviv Regev,Aviv Regev,Aviv Regev,Mario L. Suvà,Mario L. Suvà +50 more
TL;DR: This approach provides a general framework to decipher differences between classes of human tumors by decoupling cancer cell genotypes, phenotypes, and the composition of the TME.
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
Andrew S. Venteicher,Andrew S. Venteicher,Itay Tirosh,Christine Hebert,Christine Hebert,Keren Yizhak,Keren Yizhak,Cyril Neftel,Cyril Neftel,Cyril Neftel,Mariella G. Filbin,Mariella G. Filbin,Volker Hovestadt,Volker Hovestadt,Leah E. Escalante,Leah E. Escalante,McKenzie Shaw,McKenzie Shaw,Christopher Rodman,Shawn M. Gillespie,Danielle Dionne,Christina C. Luo,Hiranmayi Ravichandran,Ravindra Mylvaganam,Christopher Mount,Maristela L. Onozato,Brian V. Nahed,Hiroaki Wakimoto,William T. Curry,A. John Iafrate,Miguel Rivera,Miguel Rivera,Matthew P. Frosch,Todd R. Golub,Todd R. Golub,Todd R. Golub,Priscilla K. Brastianos,Gad Getz,Gad Getz,Anoop P. Patel,Michelle Monje,Daniel P. Cahill,Orit Rozenblatt-Rosen,David N. Louis,Bradley E. Bernstein,Bradley E. Bernstein,Aviv Regev,Aviv Regev,Aviv Regev,Mario L. Suvà,Mario L. Suvà +50 more
TL;DR: In this article, the authors dissected the influences in isocitrate dehydrogenase (IDH)-mutant gliomas by combining 14,226 single-cell RNA sequencing (RNA-seq) profiles from 16 patient samples with bulk RNA-seq profiles from 165 patient samples.
Journal ArticleDOI
A molecular single-cell lung atlas of lethal COVID-19.
Johannes C. Melms,Jana Biermann,Huachao Huang,Yiping Wang,Ajay Nair,Somnath Tagore,Igor Katsyv,André F. Rendeiro,Amit Dipak Amin,Denis Schapiro,Denis Schapiro,Chris J. Frangieh,Chris J. Frangieh,Adrienne M. Luoma,Aveline Filliol,Yinshan Fang,Hiranmayi Ravichandran,Mariano G. Clausi,George A. Alba,Meri Rogava,Sean W. Chen,Patricia Ho,Daniel T. Montoro,Daniel T. Montoro,Adam E. Kornberg,Arnold Han,Mathieu F. Bakhoum,Niroshana Anandasabapathy,Mayte Suárez-Fariñas,Samuel F. Bakhoum,Yaron Bram,Alain C. Borczuk,Xinzheng V. Guo,Jay H. Lefkowitch,Charles C. Marboe,Stephen M. Lagana,Armando Del Portillo,Emily J. Tsai,Emmanuel Zorn,Glen S. Markowitz,Robert F. Schwabe,Robert E. Schwartz,Olivier Elemento,Anjali Saqi,Hanina Hibshoosh,Jianwen Que,Benjamin Izar +46 more
TL;DR: In this paper, the authors performed single-nucleus RNA sequencing of about 116,000 nuclei from the lungs of nineteen individuals who died of COVID-19 and underwent rapid autopsy and seven control individuals.
Journal ArticleDOI
Single-Cell Analysis of the Muscle Stem Cell Hierarchy Identifies Heterotypic Communication Signals Involved in Skeletal Muscle Regeneration
Andrea J. De Micheli,Emily J. Laurilliard,Charles L. Heinke,Hiranmayi Ravichandran,Paula Fraczek,Sharon Soueid-Baumgarten,Iwijn De Vlaminck,Olivier Elemento,Benjamin D. Cosgrove +8 more
TL;DR: This study analyzes muscle regeneration in mice using single-cell RNA sequencing and shows that myogenic stem/progenitor cells exhibit heterogeneous expression of multiple Syndecan proteins in cycling myogenic cells, suggesting that Syndecans may coordinate myogenic fate regulation.
Journal ArticleDOI
The spatial landscape of lung pathology during COVID-19 progression.
André F. Rendeiro,Hiranmayi Ravichandran,Yaron Bram,Vasuretha Chandar,Junbum Kim,Cem Meydan,Jiwoon Park,Jonathan Foox,Tyler Hether,Sarah Warren,Youngmi Kim,Jason Reeves,Steven P. Salvatore,Christopher E. Mason,Eric C. Swanson,Alain C. Borczuk,Olivier Elemento,Robert E. Schwartz +17 more
TL;DR: In this article, high-parameter imaging mass cytometry was used to investigate the cellular composition and spatial architecture of acute lung injury in humans, including injuries derived from SARS-CoV-2 infection at single-cell resolution.