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Matthew Green

Researcher at University of Nottingham

Publications -  12
Citations -  542

Matthew Green is an academic researcher from University of Nottingham. The author has contributed to research in topics: DNA replication & Replisome. The author has an hindex of 9, co-authored 12 publications receiving 306 citations. Previous affiliations of Matthew Green include European Bioinformatics Institute & Massachusetts Institute of Technology.

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BioSamples database: an updated sample metadata hub

TL;DR: The BioSamples database is now the authoritative repository for all INSDC sample metadata, an ELIXIR Deposition Database for Biomolecular Data and the EMBL-EBI sample metadata hub, and the website has been redesigned to allow search and retrieval of records based on specific filters, such as ‘disease’ or ‘organism’.
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When simple sequence comparison fails: the cryptic case of the shared domains of the bacterial replication initiation proteins DnaB and DnaD

TL;DR: It is shown by NMR, in vitro mutagenesis and in vivo complementation experiments that the DNA-binding module of Bacillus subtilis DnaD comprises the YxxxIxxxW motif, the unstable helix and a portion of the mobile region, the latter two being essential for viability.
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Interactions of the Bacillus subtilis DnaE polymerase with replisomal proteins modulate its activity and fidelity.

TL;DR: In vivo data show that protein–protein interactions within the replisome modulate the activity and fidelity of DnaE, and confirm the prominent role of DnE during B. subtilis replication.