M
Maurizio Buggio
Researcher at University of Manchester
Publications - 16
Citations - 346
Maurizio Buggio is an academic researcher from University of Manchester. The author has contributed to research in topics: Mesenchymal stem cell & Stem cell. The author has an hindex of 10, co-authored 16 publications receiving 246 citations. Previous affiliations of Maurizio Buggio include Washington University in St. Louis & University of Padua.
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Journal ArticleDOI
Live Imaging of Label-Free Graphene Oxide Reveals Critical Factors Causing Oxidative-Stress-Mediated Cellular Responses
Sandra Vranic,Artur Filipe Rodrigues,Maurizio Buggio,Leon Newman,Michael R. H. White,David G. Spiller,Cyrill Bussy,Kostas Kostarelos +7 more
TL;DR: In conclusion, the lateral dimension of GO played a more important role than serum protein coating in determining biological responses to the material and time-lapse imaging of live cells interacting with label-free GO sheets can be used as a tool to assess GO-induced cytotoxicity.
Journal ArticleDOI
A novel scavenging tool for cancer biomarker discovery based on the blood-circulating nanoparticle protein corona
TL;DR: Direct evidence is offered that the in vivo NP protein corona could be deemed as a valuable tool to enrich the blood proteomic analysis and to allow the discovery of potential biomarkers in experimental disease models.
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Subnormothermic Machine Perfusion for Non–Heart-Beating Donor Liver Grafts Preservation in a Swine Model: A New Strategy to Increase the Donor Pool?
Enrico Gringeri,Pasquale Bonsignore,Domenico Bassi,Francesco D'Amico,C. Mescoli,M. Polacco,Maurizio Buggio,Roberto Luisetto,Riccardo Boetto,G. Noaro,Andrea Ferrigno,Eleonora Boncompagni,Isabel Freitas,Mariapia Vairetti,Amedeo Carraro,Daniele Neri,Umberto Cillo +16 more
TL;DR: It is confirmed that subnormothermic machine perfusion (sMP; 20°C) was able to resuscitate liver grafts from large NHBD animals and showed better histopathologic results with significantly less hepatic damage.
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Small, Thin Graphene Oxide Is Anti-inflammatory Activating Nuclear Factor Erythroid 2-Related Factor 2 via Metabolic Reprogramming
Christopher Hoyle,Jack Rivers-Auty,Eloise Lemarchand,Sandra Vranic,Emily Wang,Maurizio Buggio,Nancy J. Rothwell,Stuart M. Allan,Kostas Kostarelos,David Brough +9 more
TL;DR: The findings suggest that s-GO may be used as a valuable tool to generate further insights into inflammatory mechanisms and indicate its potential applications in biomedicine.
Journal ArticleDOI
Graphene oxide as a 2D platform for complexation and intracellular delivery of siRNA
Irene de Lázaro,Sandra Vranic,Domenico Marson,Artur Filipe Rodrigues,Maurizio Buggio,Adrián Esteban-Arranz,Mariarosa Mazza,Paola Posocco,Kostas Kostarelos +8 more
TL;DR: This study underlines the potential of non-surface modified GO flakes to act as 2D siRNA delivery platforms, without the need for cationic functionalization, but warrants further vector optimization to allow the effective release of the nucleic acid and achieve efficient gene silencing.