M
Megan E. Kizer
Researcher at Rensselaer Polytechnic Institute
Publications - 20
Citations - 634
Megan E. Kizer is an academic researcher from Rensselaer Polytechnic Institute. The author has contributed to research in topics: DNA origami & DNA nanotechnology. The author has an hindex of 9, co-authored 18 publications receiving 365 citations. Previous affiliations of Megan E. Kizer include Massachusetts Institute of Technology & Binghamton University.
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Journal ArticleDOI
Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition.
Paul S. Kwon,Paul S. Kwon,Paul S. Kwon,Shaokang Ren,Seok Joon Kwon,Megan E. Kizer,Lili Kuo,Mo Xie,Dan Zhu,Feng Zhou,Fuming Zhang,Domyoung Kim,Keith Fraser,Laura D. Kramer,Nadrian C. Seeman,Jonathan S. Dordick,Robert J. Linhardt,Jie Chao,Xing Wang,Xing Wang +19 more
TL;DR: This work demonstrates a designer DNA nanostructure that can act as a template to display multiple binding motifs with precise spatial pattern-recognition properties, and shows that this approach can confer exceptional sensing and potent viral inhibitory capabilities.
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Tip-Enhanced Raman Imaging of Single-Stranded DNA with Single Base Resolution
Zhe He,Zehua Han,Megan E. Kizer,Robert J. Linhardt,Xing Wang,Alexander M. Sinyukov,Jizhou Wang,Volker Deckert,Alexei V. Sokolov,Alexei V. Sokolov,Jonathan Hu,Marlan O. Scully,Marlan O. Scully +12 more
TL;DR: The real-time profiling of a ssDNA configuration is demonstrated and it is anticipated that this technique can be extended to the high-resolution imaging of various nanostructures as well as the direct sequencing of other important biopolymers including RNA, polysaccharides, and polypeptides.
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Beyond the Fold: Emerging Biological Applications of DNA Origami.
TL;DR: The DNA origami technique has already found widespread use in a variety of emerging biological applications such as biosensing, enzyme cascades, biomolecular analysis, biomimetics, and drug delivery.
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Paranemic Crossover DNA: There and Back Again
Xing Wang,Arun Richard Chandrasekaran,Zhiyong Shen,Yoel P. Ohayon,Tong Wang,Megan E. Kizer,Ruojie Sha,Chengde Mao,Hao Yan,Xiaoping Zhang,Shiping Liao,Baoquan Ding,Banani Chakraborty,Natasha Jonoska,Dong Niu,Hongzhou Gu,Jie Chao,Xiang Gao,Yuhang Li,Tanashaya Ciengshin,Nadrian C. Seeman +20 more
TL;DR: The PX motif has recently found a new role directly in basic biology, by possibly serving as the molecular structure for double-stranded DNA homology recognition, a prominent feature of molecular biology and essential for many crucial biological processes.
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Intracellular Delivery of Nanomaterials via an Inertial Microfluidic Cell Hydroporator
TL;DR: This hydroporation method shows superior delivery efficiency, is high-throughput, and has high controllability; moreover, its extremely simple and low-cost operation provides a powerful and practical strategy in the applications of cellular imaging, biomanufacturing, cell-based therapies, regenerative medicine, and disease diagnosis.