F
Fuming Zhang
Researcher at Rensselaer Polytechnic Institute
Publications - 26
Citations - 1719
Fuming Zhang is an academic researcher from Rensselaer Polytechnic Institute. The author has contributed to research in topics: Chondroitin sulfate & Heparan sulfate. The author has an hindex of 16, co-authored 26 publications receiving 1416 citations. Previous affiliations of Fuming Zhang include University of Leeds & New York University.
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Journal ArticleDOI
Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members
Regina Goetz,Andrew Beenken,Omar A. Ibrahimi,Juliya Kalinina,Shaun K. Olsen,Anna V. Eliseenkova,Chong Feng Xu,Thomas A. Neubert,Fuming Zhang,Fuming Zhang,Robert J. Linhardt,Xijie Yu,Kenneth E. White,Takeshi Inagaki,Steven A. Kliewer,Masaya Yamamoto,Hiroshi Kurosu,Yasushi Ogawa,Makoto Kuro-o,Beate Lanske,Mohammed S. Razzaque,Moosa Mohammadi +21 more
TL;DR: The crystal structures of FGF19 alone and FGF23 in complex with sucrose octasulfate, a disaccharide chemically related to heparin, are presented, showing that Klotho/βKlotho have evolved as a compensatory mechanism for the poor ability ofHeparin/heparan sulfate to promote binding of F GF19, -21, and -23 to their cognate receptors.
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Kinetic Model for FGF, FGFR, and Proteoglycan Signal Transduction Complex Assembly†
TL;DR: The weak binding affinity of the FGFR1-heparin interaction suggests that in this model, FGFR and HSPG are unbound in the absence of FGF ligand, and a model for the stepwise assembly of a ternary FGF-FGFR-HSPG complex is proposed.
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Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition.
Paul S. Kwon,Paul S. Kwon,Paul S. Kwon,Shaokang Ren,Seok Joon Kwon,Megan E. Kizer,Lili Kuo,Mo Xie,Dan Zhu,Feng Zhou,Fuming Zhang,Domyoung Kim,Keith Fraser,Laura D. Kramer,Nadrian C. Seeman,Jonathan S. Dordick,Robert J. Linhardt,Jie Chao,Xing Wang,Xing Wang +19 more
TL;DR: This work demonstrates a designer DNA nanostructure that can act as a template to display multiple binding motifs with precise spatial pattern-recognition properties, and shows that this approach can confer exceptional sensing and potent viral inhibitory capabilities.
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Development of bioreactor systems for decolorization of Orange II using white rot fungus
TL;DR: Three different reactor configurations were designed and tested for decolorization of an azo dye, Orange II, with white rot fungus and all the bioreactors showed high and stableDecolorization activity in long-term operation.
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Decolourisation of Orange II by a Wood-Rotting Fungus
TL;DR: In this paper, the decolourisation of Orange II by a wood-rotting fungus has been studied, and it was found that Fungus F29 could effectively decolorise Orange II especially when grown as pelleted mycelia under agitated conditions.