M
Mehrdad M. Moshrefi
Researcher at Schering-Plough
Publications - 2
Citations - 3430
Mehrdad M. Moshrefi is an academic researcher from Schering-Plough. The author has contributed to research in topics: Receptor & Interleukin-21 receptor. The author has an hindex of 2, co-authored 2 publications receiving 3117 citations.
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Journal ArticleDOI
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
Jochen Schmitz,Alexander Owyang,Elizabeth R. Oldham,Yaoli Song,Erin Murphy,Terril K. McClanahan,Gerard Zurawski,Mehrdad M. Moshrefi,Jinzhong Qin,Xiaoxia Li,Daniel M. Gorman,J. Fernando Bazan,Robert A. Kastelein +12 more
TL;DR: A member of theIL-1 family, IL-33, which mediates its biological effects via IL-1 receptor ST 2, activates NF-kappaB and MAP kinases, and drives production of T(H)2-associated cytokines from in vitro polarized T( H)2 cells is reported.
Journal ArticleDOI
The CD200 Receptor Is a Novel and Potent Regulator of Murine and Human Mast Cell Function
Holly Cherwinski,Craig A. Murphy,Barbara L. Joyce,M. Bigler,Yaoli S. Song,Sandra Zurawski,Mehrdad M. Moshrefi,Daniel M. Gorman,Kathy L. Miller,Shuli Zhang,Jonathan D. Sedgwick,Joseph H. Phillips +11 more
TL;DR: It is concluded that CD200R represents a novel and potent inhibitory receptor that can be targeted in vivo to regulate mast cell-dependent pathologies.