Michael Kjaer

TL;DR: In conclusion, ERT was associated with enhanced synthesis of type I collagen in the skeletal muscle in response to acute exercise, indicating that the availability of estrogen in postmenopausal women is important for repair of muscle damage or remodeling of the connective tissue within the skeletal Muscle after exercise.

TL;DR: The resting plasma level of transforming growth factor-β-1 was stable over time when blood samples were treated appropriately, and exercise increased the plasma concentration, perhaps indicating a release from mechanically loaded tissues.

TL;DR: The importance of regular mechanical load in order to preserve the stabilizing role of the connective tissue for the overall function of the musculoskeletal system in both daily activity and exercise is illustrated.

TL;DR: It is suggested that tendinopathy pathogenesis represents a disturbed tissue homeostasis with fluid accumulation and is likely induced by repeated mechanical overloading rather than a partial rupture of the tendon.

TL;DR: Carbon‐14 bomb pulse dating shows that tendinopathy is preceded by years of abnormally high collagen turnover, which suggests that either the symptoms of tendinopathic represent a late phase of a very prolonged disease process, or an abnormallyhigh collagen exchange could be a risk factor for tendon disorders rather than being a result of disease.