Michael Niehues

TL;DR: The current review attempts to give an overview on the potential of such plant-derived natural products as antiprotozoal leads and/or drugs in the fight against NTDs.

TL;DR: This contribution aims to review the most important mechanisms of various abiotic and biotic interactions, such as pathogenic microorganisms and herbivory, by which plants respond to exogenous influences, and will also report on time-scale variable influences on secondary metabolite profiles.

TL;DR: The data recorded by the German naturalist von Martius represent a rich, unexplored source of information about the traditional uses of Brazilian plants.

TL;DR: The biomimetic model with a manganese salen complex has evidenced its use as a valuable tool to predict and elucidate the in vivo phase I metabolism of lapachol and possibly also of other bioactive natural compounds.

TL;DR: LAP could be considered as a potential immunosuppressive lead candidate with potential therapeutic implications for RA, and a binding model of interaction is proposed and support the ability of LAP to inhibit DHODH, decreasing lymphocyte proliferation and attenuating the severity of experimental autoimmune arthritis.