M
Michael Pfeilstöcker
Researcher at Medical University of Vienna
Publications - 119
Citations - 7063
Michael Pfeilstöcker is an academic researcher from Medical University of Vienna. The author has contributed to research in topics: Myelodysplastic syndromes & International Prognostic Scoring System. The author has an hindex of 32, co-authored 113 publications receiving 6022 citations.
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Journal ArticleDOI
Revised International Prognostic Scoring System for Myelodysplastic Syndromes
Peter L. Greenberg,Heinz Tuechler,Julie Schanz,Guillermo Sanz,Guillermo Garcia-Manero,Francesc Solé,John M. Bennett,David T. Bowen,Pierre Fenaux,François Dreyfus,Hagop M. Kantarjian,Andrea Kuendgen,Alessandro Levis,Luca Malcovati,Mario Cazzola,Jaroslav Cermak,Christa Fonatsch,Michelle M. Le Beau,Marilyn L. Slovak,Otto Krieger,Michael Luebbert,Jaroslaw P. Maciejewski,Silvia Maria Meira Magalhães,Yasushi Miyazaki,Michael Pfeilstöcker,Mikkael A. Sekeres,Wolfgang R. Sperr,Reinhard Stauder,Sudhir Tauro,Peter Valent,Teresa Vallespi,Arjan A. van de Loosdrecht,Ulrich Germing,Detlef Haase +33 more
TL;DR: This revised IPSS-R comprehensively integrated the numerous known clinical features into a method analyzing MDS patient prognosis more precisely than the initial IPSS and should prove beneficial for predicting the clinical outcomes of untreated MDS patients and aiding design and analysis of clinical trials in this disease.
Journal ArticleDOI
New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: evidence from a core dataset of 2124 patients.
Detlef Haase,Ulrich Germing,Julie Schanz,Michael Pfeilstöcker,Thomas Nösslinger,Barbara Hildebrandt,Andrea Kündgen,Michael Lübbert,Regina Kunzmann,Aristoteles Giagounidis,Carlo Aul,Lorenz Trümper,Otto Krieger,Reinhard Stauder,Thomas Müller,Friedrich Wimazal,Peter Valent,Christa Fonatsch,Christian Steidl +18 more
TL;DR: A large, unique database that includes morphologic, clinical, cytogenetic, and follow-up data from 2124 patients with myelodysplastic syndromes (MDSs) offers new insights into the prognostic significance of rare chromosomal abnormalities and specific karyotypic combinations in MDS.
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New Comprehensive Cytogenetic Scoring System for Primary Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia After MDS Derived From an International Database Merge
Julie Schanz,Heinz Tüchler,Francesc Solé,Mar Mallo,E. Luño,José Cervera,Isabel Granada,Barbara Hildebrandt,Marilyn L. Slovak,Kazuma Ohyashiki,Christian Steidl,Christa Fonatsch,Michael Pfeilstöcker,Thomas Nösslinger,Peter Valent,Aristoteles Giagounidis,Carlo Aul,Michael Lübbert,Reinhard Stauder,Otto Krieger,Guillermo Garcia-Manero,Stefan Faderl,Sherry Pierce,Michelle M. Le Beau,John M. Bennett,Peter L. Greenberg,Ulrich Germing,Detlef Haase +27 more
TL;DR: A new and comprehensive cytogenetic scoring system based on an international data collection of 2,902 patients with primary MDS and oligoblastic acute myeloid leukemia (AML) after MDS treated with supportive care only is proposed, providing clear prognostic classification in 91% of all patients.
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Definitions and standards in the diagnosis and treatment of the myelodysplastic syndromes: Consensus statements and report from a working conference
Peter Valent,Hans-Peter Horny,John M. Bennett,Christa Fonatsch,Ulrich Germing,Peter L. Greenberg,Torsten Haferlach,Detlef Haase,H. J. Kolb,Otto Krieger,Michael R. Loken,Arjan A. van de Loosdrecht,Kiyoyuki Ogata,Alberto Orfao,Michael Pfeilstöcker,Björn Rüter,Wolfgang R. Sperr,Reinhard Stauder,Denise A. Wells +18 more
TL;DR: Concerning the diagnostic interface, minimal diagnostic criteria for MDS are proposed, and for patients with unexplained cytopenia who do not fulfill these criteria, the term 'idiopathic cy topenia of uncertain significance' (ICUS) is suggested.
Journal ArticleDOI
Refinement of the international prognostic scoring system (IPSS) by including LDH as an additional prognostic variable to improve risk assessment in patients with primary myelodysplastic syndromes (MDS).
Ulrich Germing,Barbara Hildebrandt,Michael Pfeilstöcker,Thomas Nösslinger,Peter Valent,Christa Fonatsch,Michael Lübbert,Detlef Haase,Christian Steidl,Otto Krieger,Reinhard Stauder,Aristoteles Giagounidis,Corinna Strupp,Andrea Kündgen,T Mueller,Rainer Haas,Norbert Gattermann,Carlo Aul +17 more
TL;DR: It is proposed that the IPSS+LDH score should improve clinical decision-making and facilitate proper risk stratification in clinical trials and be used to identify MDS patients with unfavorable prognosis within the low and intermediate IPSS risk groups.