J
Julie Schanz
Researcher at University of Göttingen
Publications - 79
Citations - 5365
Julie Schanz is an academic researcher from University of Göttingen. The author has contributed to research in topics: Myelodysplastic syndromes & International Prognostic Scoring System. The author has an hindex of 19, co-authored 72 publications receiving 4332 citations.
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Journal ArticleDOI
Revised International Prognostic Scoring System for Myelodysplastic Syndromes
Peter L. Greenberg,Heinz Tuechler,Julie Schanz,Guillermo Sanz,Guillermo Garcia-Manero,Francesc Solé,John M. Bennett,David T. Bowen,Pierre Fenaux,François Dreyfus,Hagop M. Kantarjian,Andrea Kuendgen,Alessandro Levis,Luca Malcovati,Mario Cazzola,Jaroslav Cermak,Christa Fonatsch,Michelle M. Le Beau,Marilyn L. Slovak,Otto Krieger,Michael Luebbert,Jaroslaw P. Maciejewski,Silvia Maria Meira Magalhães,Yasushi Miyazaki,Michael Pfeilstöcker,Mikkael A. Sekeres,Wolfgang R. Sperr,Reinhard Stauder,Sudhir Tauro,Peter Valent,Teresa Vallespi,Arjan A. van de Loosdrecht,Ulrich Germing,Detlef Haase +33 more
TL;DR: This revised IPSS-R comprehensively integrated the numerous known clinical features into a method analyzing MDS patient prognosis more precisely than the initial IPSS and should prove beneficial for predicting the clinical outcomes of untreated MDS patients and aiding design and analysis of clinical trials in this disease.
Journal ArticleDOI
New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: evidence from a core dataset of 2124 patients.
Detlef Haase,Ulrich Germing,Julie Schanz,Michael Pfeilstöcker,Thomas Nösslinger,Barbara Hildebrandt,Andrea Kündgen,Michael Lübbert,Regina Kunzmann,Aristoteles Giagounidis,Carlo Aul,Lorenz Trümper,Otto Krieger,Reinhard Stauder,Thomas Müller,Friedrich Wimazal,Peter Valent,Christa Fonatsch,Christian Steidl +18 more
TL;DR: A large, unique database that includes morphologic, clinical, cytogenetic, and follow-up data from 2124 patients with myelodysplastic syndromes (MDSs) offers new insights into the prognostic significance of rare chromosomal abnormalities and specific karyotypic combinations in MDS.
Journal ArticleDOI
New Comprehensive Cytogenetic Scoring System for Primary Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia After MDS Derived From an International Database Merge
Julie Schanz,Heinz Tüchler,Francesc Solé,Mar Mallo,E. Luño,José Cervera,Isabel Granada,Barbara Hildebrandt,Marilyn L. Slovak,Kazuma Ohyashiki,Christian Steidl,Christa Fonatsch,Michael Pfeilstöcker,Thomas Nösslinger,Peter Valent,Aristoteles Giagounidis,Carlo Aul,Michael Lübbert,Reinhard Stauder,Otto Krieger,Guillermo Garcia-Manero,Stefan Faderl,Sherry Pierce,Michelle M. Le Beau,John M. Bennett,Peter L. Greenberg,Ulrich Germing,Detlef Haase +27 more
TL;DR: A new and comprehensive cytogenetic scoring system based on an international data collection of 2,902 patients with primary MDS and oligoblastic acute myeloid leukemia (AML) after MDS treated with supportive care only is proposed, providing clear prognostic classification in 91% of all patients.
Journal ArticleDOI
Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes
Elsa Bernard,Yasuhito Nannya,Robert P. Hasserjian,Sean M. Devlin,Heinz Tuechler,Juan S. Medina-Martinez,Tetsuichi Yoshizato,Yusuke Shiozawa,Ryunosuke Saiki,Luca Malcovati,Max Levine,Juan E. Arango,Yangyu Zhou,Francesc Solé,Catherine Cargo,Detlef Haase,Maria Creignou,Ulrich Germing,Yanming Zhang,Gunes Gundem,Araxe Sarian,Arjan A. van de Loosdrecht,Martin Jädersten,Magnus Tobiasson,Olivier Kosmider,Matilde Y. Follo,Felicitas Thol,Ronald Feitosa Pinheiro,Valeria Santini,Ioannis Kotsianidis,Jacqueline Boultwood,Fabio P.S. Santos,Julie Schanz,Senji Kasahara,Takayuki Ishikawa,Hisashi Tsurumi,Akifumi Takaori-Kondo,Toru Kiguchi,Chantana Polprasert,John M. Bennett,Virginia M. Klimek,Michael R. Savona,Monika Belickova,Christina Ganster,Laura Palomo,Guillermo Sanz,Lionel Ades,Matteo G. Della Porta,Alexandra Smith,Yesenia Werner,Minal Patel,Agnes Viale,Katelynd Vanness,Donna Neuberg,Kristen E. Stevenson,Kamal Menghrajani,Kelly L. Bolton,Pierre Fenaux,Andrea Pellagatti,Uwe Platzbecker,Michael Heuser,Peter Valent,Shigeru Chiba,Yasushi Miyazaki,Carlo Finelli,Maria Teresa Voso,Lee Yung Shih,Michaela Fontenay,Joop H. Jansen,José Cervera,Yoshiko Atsuta,Norbert Gattermann,Benjamin L. Ebert,Rafael Bejar,Peter L. Greenberg,Mario Cazzola,Eva Hellström-Lindberg,Seishi Ogawa,Elli Papaemmanuil +78 more
TL;DR: Clinical sequencing across a large prospective cohort of patients with myelodysplasic syndrome uncovers distinct associations between the mono- and biallelic states of TP53 and clinical presentation.
Journal ArticleDOI
Proposed minimal diagnostic criteria for myelodysplastic syndromes (MDS) and potential pre-MDS conditions
Peter Valent,Attilio Orazi,David P. Steensma,Benjamin L. Ebert,Detlef Haase,Luca Malcovati,Arjan A. van de Loosdrecht,Torsten Haferlach,Theresia M. Westers,Denise A. Wells,Aristoteles Giagounidis,Michael R. Loken,Alberto Orfao,Michael Lübbert,Arnold Ganser,Wolf-Karsten Hofmann,Kiyoyuki Ogata,Julie Schanz,Marie C. Béné,Gregor Hoermann,Wolfgang R. Sperr,Karl Sotlar,Peter Bettelheim,Reinhard Stauder,Michael Pfeilstöcker,Hans-Peter Horny,Ulrich Germing,Peter L. Greenberg,John M. Bennett +28 more
TL;DR: Diagnostic standards to delineate between ´normal´, pre-MDS, and MDS are proposed and these standards and criteria should facilitate diagnostic and prognostic evaluations in clinical studies as well as in clinical practice.