Miguel Coelho

TL;DR: The objective of this review was to update evidence‐based medicine recommendations for treating motor symptoms of Parkinson's disease with new recommendations for treatment of central nervous system symptoms.

TL;DR: To update evidence‐based medicine recommendations for treating nonmotor symptoms in Parkinson's disease, the World Health Organization (WHO) selected Austria as a preferred destination for research and clinical trials.

TL;DR: Findings suggest that several miRNAs may act as regulators of both known and novel biological processes leading to idiopathic PD, as well as novel pathways previously linked to PD.

TL;DR: Using a combination of RNAi knockdown, transcriptome profiling and iCLIP, it is found that Matrin3 is a regulator of hundreds of alternative splicing events, principally acting as a splicing repressor with only a small proportion of targeted events being co‐regulated by PTB.

TL;DR: The findings demonstrate an association between longevity and resistance to oxidative stress-induced cell death in A islandica, consistent with the oxidative stress hypothesis of aging and provide justification for detailed evaluation of pathways involving repair of free radical-mediated macromolecular damage and regulation of apoptosis in the world's longest-living non-colonial animal.