M
Min Zhao
Researcher at Xiamen University
Publications - 20
Citations - 940
Min Zhao is an academic researcher from Xiamen University. The author has contributed to research in topics: Epitope & Antibody. The author has an hindex of 7, co-authored 13 publications receiving 742 citations. Previous affiliations of Min Zhao include National Institutes of Health.
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Journal ArticleDOI
Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody
Jason S. McLellan,Man Chen,Sherman Leung,Kevin W. Graepel,Xiulian Du,Yongping Yang,Tongqing Zhou,Ulrich Baxa,Etsuko Yasuda,Tim Beaumont,Azad Kumar,Kayvon Modjarrad,Zizheng Zheng,Min Zhao,Ningshao Xia,Peter D. Kwong,Barney S. Graham +16 more
TL;DR: Preference-specific antibodies that were substantially more potent than the prophylactic antibody palivizumab were identified, which should enable design of improved vaccine antigens and define new targets for passive prevention of RSV-induced disease.
Journal ArticleDOI
Role of heat-shock protein 90 in hepatitis E virus capsid trafficking.
TL;DR: It was concluded that HSP90 plays a crucial role in the intracellular transportation of viral capsids in the early stage of HEV infection.
Journal ArticleDOI
Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein.
Daiyin Tian,Michael B. Battles,Syed M. Moin,Man Chen,Kayvon Modjarrad,Azad Kumar,Masaru Kanekiyo,Kevin W. Graepel,Noor M. Taher,Anne L. Hotard,Martin L. Moore,Min Zhao,Zizheng Zheng,Ningshao Xia,Jason S. McLellan,Barney S. Graham +15 more
TL;DR: It is shown that unlike D25, 5C4 preferentially neutralizes subtype A viruses, which improves the understanding of subtype-specific immunity and the neutralization breadth requirements of next-generation antibodies, and contributes to the design of broadly protective RSV vaccines.
Journal ArticleDOI
A Comprehensive Study of Neutralizing Antigenic Sites on the Hepatitis E Virus (HEV) Capsid by Constructing, Clustering, and Characterizing a Tool Box.
Min Zhao,Xiao-Jing Li,Zi-Min Tang,Fan Yang,Si-Ling Wang,Wei Cai,Ke Zhang,Ningshao Xia,Zizheng Zheng +8 more
TL;DR: This study used the statistical software SPSS to analyze cELISA (competitive ELISA) data to classify monoclonal antibodies (mAbs), which recognized conformational epitopes on E2s domain, which helped further the understanding of protective mechanisms induced by the HEV vaccine.
Journal ArticleDOI
A novel linear neutralizing epitope of hepatitis E virus
Zi-Min Tang,Ming Tang,Min Zhao,Gui-Ping Wen,Fan Yang,Wei Cai,Si-Ling Wang,Zizheng Zheng,Ningshao Xia +8 more
TL;DR: It is shown herein that this epitope could induce a neutralizing antibody response against HEV in mice and could protect rhesus monkeys from HEV infection and provided additional insight of HEV vaccine.