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Nan Chen
Researcher at Shanghai Jiao Tong University
Publications - 2
Citations - 576
Nan Chen is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Nephropathy & Genome-wide association study. The author has an hindex of 2, co-authored 2 publications receiving 507 citations.
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Journal ArticleDOI
Genome-wide association study identifies susceptibility loci for IgA nephropathy
Ali G. Gharavi,Krzysztof Kiryluk,Murim Choi,Yifu Li,Ping Hou,Ping Hou,Jingyuan Xie,Jingyuan Xie,Simone Sanna-Cherchi,Clara J. Men,Bruce A. Julian,Robert J. Wyatt,Jan Novak,John Cijiang He,Haiyan Wang,Jicheng Lv,Li Zhu,Weiming Wang,Zhaohui Wang,Kasuhito Yasuno,Murat Gunel,Shrikant Mane,Sheila Umlauf,Irina Tikhonova,Isabel Beerman,Silvana Savoldi,Riccardo Magistroni,Gian Marco Ghiggeri,Monica Bodria,Francesca Lugani,Francesca Lugani,Pietro Ravani,Claudio Ponticelli,Landino Allegri,Giuliano Boscutti,Giovanni M. Frascà,Alessandro Amore,Licia Peruzzi,Rosanna Coppo,Claudia Izzi,Battista Fabio Viola,Prati E,Maurizio Salvadori,Renzo Mignani,Loreto Gesualdo,Francesca Bertinetto,Paola Mesiano,Antonio Amoroso,Francesco Scolari,Nan Chen,Hong Zhang,Richard P. Lifton +51 more
TL;DR: Three independent loci in the major histocompatibility complex, as well as a common deletion of CFHR1 and CFHR3 at chromosome 1q32 and a locus at chromosome 22q12 that each surpassed genome-wide significance, explain 4–7% of the disease variance and up to a tenfold variation in interindividual risk.
Journal ArticleDOI
Role of the retinoic acid receptor-α in HIV-associated nephropathy
Krishna Ratnam,Xiaobei Feng,Peter Y. Chuang,Vikram Verma,Ting-Chi Lu,Jinshan Wang,Yuanmeng Jin,Eduardo F. Farias,Joseph L. Napoli,Nan Chen,Lewis Kaufman,Tomoko Takano,Vivette D. D'Agati,Paul E. Klotman,John Cijiang He,John Cijiang He +15 more
TL;DR: It is reported that Am 580, a water-soluble RARα-specific agonist, attenuated proteinuria, glomerosclerosis, and podocyte proliferation, and restored podocyte differentiation markers in kidneys of Tg26 mice, confirming the hypothesis that Am580 acts through RAR α.