Weiming Wang

TL;DR: The prevalence of chronic kidney disease in China was high in north and southwest and southwest regions compared with other regions, and economic development was independently associated with the presence of albuminuria.

TL;DR: Three independent loci in the major histocompatibility complex, as well as a common deletion of CFHR1 and CFHR3 at chromosome 1q32 and a locus at chromosome 22q12 that each surpassed genome-wide significance, explain 4–7% of the disease variance and up to a tenfold variation in interindividual risk.

TL;DR: All the factors including age, central obesity, hypertension, diabetes, anaemia, hyperuricaemia and nephrolithiasis are positively correlated with the development of CKD in the studied subjects.

TL;DR: The data indicate that IgAN patients with higher systolic blood pressure, lower eGFR, hemoglobin, and albumin levels at baseline are at a greatest risk of progression to ESRD, and a 4-variable equation of a clinical risk score for disease progression is developed.

TL;DR: The findings highlight an unusual genetic architecture of MN, with four loci and their interactions accounting for nearly one-third of the disease risk.