N
Naohiro Nishida
Researcher at Osaka University
Publications - 75
Citations - 3353
Naohiro Nishida is an academic researcher from Osaka University. The author has contributed to research in topics: Cancer & Colorectal cancer. The author has an hindex of 28, co-authored 71 publications receiving 2782 citations. Previous affiliations of Naohiro Nishida include Kyushu University.
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Journal ArticleDOI
MicroRNA-125a-5p Is an Independent Prognostic Factor in Gastric Cancer and Inhibits the Proliferation of Human Gastric Cancer Cells in Combination with Trastuzumab
Naohiro Nishida,Koshi Mimori,Muller Fabbri,Takehiko Yokobori,Tomoya Sudo,Fumiaki Tanaka,Kohei Shibata,Hideshi Ishii,Hideshi Ishii,Yuichiro Doki,Masaki Mori +10 more
TL;DR: In vitro assays showed that ERBB2 is a direct target of miR-125a-5p, which potently suppressed the proliferation of gastric cancer cells, and, interestingly, the growth inhibitory effect was enhanced in combination with trastuzumab.
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Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis
Takehiko Yokobori,Hisae Iinuma,Teppei Shimamura,Seiya Imoto,Keishi Sugimachi,Hideshi Ishii,Masaaki Iwatsuki,Daisuke Ota,Masahisa Ohkuma,Takeshi Iwaya,Naohiro Nishida,Ryunosuke Kogo,Tomoya Sudo,Fumiaki Tanaka,Kohei Shibata,Hiroyuki Toh,Tetsuya Sato,Graham F. Barnard,Takeo Fukagawa,Seiichiro Yamamoto,Hayao Nakanishi,Shin Sasaki,Satoru Miyano,Toshiaki Watanabe,Hiroyuki Kuwano,Koshi Mimori,Klaus Pantel,Masaki Mori +27 more
TL;DR: PLS3-positive CTC was independently associated with prognosis in the training set and the validation set, and it possesses significant prognostic value.
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Oncogene c-Myc promotes epitranscriptome m6A reader YTHDF1 expression in colorectal cancer.
Yujiro Nishizawa,Masamitsu Konno,Ayumu Asai,Jun Koseki,Koichi Kawamoto,Norikatsu Miyoshi,Hidekazu Takahashi,Naohiro Nishida,Naotsugu Haraguchi,Daisuke Sakai,Toshihiro Kudo,Taishi Hata,Chu Matsuda,Tsunekazu Mizushima,Taroh Satoh,Yuichiro Doki,Masaki Mori,Hideshi Ishii +17 more
TL;DR: The in vitro study showed that the knockdown of YTHDF1 resulted in the suppression of cancer proliferation and sensitization to the exposure of anticancer drugs such as fluorouracil and oxaliplatin, suggesting that m6A reader Ythdf1 plays a significant role in colorectal cancer progression.
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Downregulation of miR-144 is associated with colorectal cancer progression via activation of mTOR signaling pathway
Takeshi Iwaya,Takeshi Iwaya,Takehiko Yokobori,Naohiro Nishida,Ryunosuke Kogo,Tomoya Sudo,Fumiaki Tanaka,Kohei Shibata,Genta Sawada,Yusuke Takahashi,Masahisa Ishibashi,Go Wakabayashi,Masaki Mori,Koshi Mimori +13 more
TL;DR: Investigation of the clinicopathologic magnitude of the mTOR pathway regulating microRNA, miR-144 in colorectal cancer (CRC) cases and the correlation between CRC prognosis and the expression of 16 genes in the Akt/mTOR pathway indicated that high expression of Rictor was associated with poor prognosis of CRC.
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Microarray Analysis of Colorectal Cancer Stromal Tissue Reveals Upregulation of Two Oncogenic miRNA Clusters
Naohiro Nishida,Makoto Nagahara,Tetsuya Sato,Koshi Mimori,Tomoya Sudo,Fumiaki Tanaka,Kohei Shibata,Hideshi Ishii,Hideshi Ishii,Kenichi Sugihara,Yuichiro Doki,Masaki Mori +11 more
TL;DR: The finding that stromal miRNA expression levels were associated with clinicopathologic factors suggests the possibility that miRNAs in cancer stroma are crucially involved in cancer progression.