T
Tetsuya Sato
Researcher at Kyushu University
Publications - 20
Citations - 1024
Tetsuya Sato is an academic researcher from Kyushu University. The author has contributed to research in topics: Cancer & Phylogenetic tree. The author has an hindex of 12, co-authored 20 publications receiving 944 citations. Previous affiliations of Tetsuya Sato include Kitasato University & Kyoto University.
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Journal ArticleDOI
Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis
Takehiko Yokobori,Hisae Iinuma,Teppei Shimamura,Seiya Imoto,Keishi Sugimachi,Hideshi Ishii,Masaaki Iwatsuki,Daisuke Ota,Masahisa Ohkuma,Takeshi Iwaya,Naohiro Nishida,Ryunosuke Kogo,Tomoya Sudo,Fumiaki Tanaka,Kohei Shibata,Hiroyuki Toh,Tetsuya Sato,Graham F. Barnard,Takeo Fukagawa,Seiichiro Yamamoto,Hayao Nakanishi,Shin Sasaki,Satoru Miyano,Toshiaki Watanabe,Hiroyuki Kuwano,Koshi Mimori,Klaus Pantel,Masaki Mori +27 more
TL;DR: PLS3-positive CTC was independently associated with prognosis in the training set and the validation set, and it possesses significant prognostic value.
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The inference of protein–protein interactions by co-evolutionary analysis is improved by excluding the information about the phylogenetic relationships
TL;DR: A novel method to predict protein-protein interactions from co-evolutionary information in the framework of the mirror tree method was developed, and it drastically reduced the number of false positives in the prediction.
Journal ArticleDOI
Loss of FBXW7, a cell cycle regulating gene, in colorectal cancer: Clinical significance
Masaaki Iwatsuki,Koshi Mimori,Hideshi Ishii,Takehiko Yokobori,Yasushi Takatsuno,Tetsuya Sato,Hiroyuki Toh,Ichiro Onoyama,Keiichi I. Nakayama,Hideo Baba,Masaki Mori +10 more
TL;DR: The expression level of FBXW7 in colorectal cancer (CRC) cases was determined, correlated those values with clinicopathologic features, and the molecular mechanism of reduced expression of FBZ7 in CRC cells in vitro was characterized.
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Notch-Hes1 pathway is required for the development of IL-17-producing γδ T cells.
Kensuke Shibata,Hisakata Yamada,Tetsuya Sato,Takashi Dejima,Masataka Nakamura,Tomokatsu Ikawa,Hiromitsu Hara,Sho Yamasaki,Ryoichiro Kageyama,Yoichiro Iwakura,Hiroshi Kawamoto,Hiroyuki Toh,Yasunobu Yoshikai +12 more
TL;DR: It is shown that intrathymic development of the naturally occurring IL-17-producing γδ T cells is independent of STAT3 and partly dependent on RORγt, and Hes1, one of the basic helix-loop-helix proteins involved in Notch signaling, is critically involved in the development of IL- 17-producing Greek T cells.
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Protective role of the leukotriene B4 receptor BLT2 in murine inflammatory colitis
Yoshiko Iizuka,Toshiaki Okuno,Kazuko Saeki,Hiroshi Uozaki,Shinji Okada,Takumi Misaka,Tetsuya Sato,Hiroyuki Toh,Masahisa Fukayama,Naoki Takeda,Yoshihiro Kita,Takao Shimizu,Motonao Nakamura,Takehiko Yokomizo,Takehiko Yokomizo +14 more
TL;DR: BLT2 is expressed in colon cryptic cells and appears to protect against DSS-induced colitis, possibly by enhancing barrier function in epithelial cells of the colon.