Takeshi Yagi

Researcher at Osaka University

Publications - 207

Citations - 20054

Takeshi Yagi is an academic researcher from Osaka University. The author has contributed to research in topics: Protocadherin & FYN. The author has an hindex of 66, co-authored 201 publications receiving 19130 citations. Previous affiliations of Takeshi Yagi include University of Colorado Denver & Graduate University for Advanced Studies.

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Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

Hiroyuki Tamemoto, +18 more

- 10 Nov 1994 -

Nature

TL;DR: The data suggest that mice homozygous for targeted disruption of the IRS-1 gene were born alive but were retarded in embryonal and postnatal growth and the exis-tence of both IRS- 1-dependent and IRS-2-independent pathways for signal transduction of insulin and IGFs is suggested.

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A requirement for neuropilin-1 in embryonic vessel formation

Takahiko Kawasaki, +6 more

- 01 Nov 1999 -

Development

TL;DR: The vascular defects induced by neuropilin-1 deficiency in mouse embryos suggest that neurop Pilin 1 plays roles in embryonic vessel formation, as well as nerve fiber guidance in embryogenesis.

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Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor ε1 subunit

Kenji Sakimura, +11 more

- 12 Jan 1995 -

Nature

TL;DR: It is shown that targeted disruption of the mouse εl subunit gene resulted in significant reduction of the NMDA receptor channel current and long-term potentiation at the hippocampal CA1 synapses, which supports the notion that the NMda receptor channel-dependent synaptic plasticity is the cellular basis of certain forms of learning.

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