N
Natalia L. S. Machado
Researcher at Beth Israel Deaconess Medical Center
Publications - 18
Citations - 421
Natalia L. S. Machado is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: Glutamatergic & Median preoptic nucleus. The author has an hindex of 9, co-authored 14 publications receiving 319 citations. Previous affiliations of Natalia L. S. Machado include Harvard University & Universidade Federal de Minas Gerais.
Papers
More filters
Journal ArticleDOI
A hypothalamic circuit for the circadian control of aggression.
William D. Todd,Henning Fenselau,Henning Fenselau,Joshua L. Wang,Rong Zhang,Rong Zhang,Natalia L. S. Machado,Natalia L. S. Machado,Anne Venner,Rebecca Y. Broadhurst,Satvinder Kaur,Timothy Lynagh,David P. Olson,Bradford B. Lowell,Patrick M. Fuller,Clifford B. Saper +15 more
TL;DR: A daily rhythm in aggression propensity in male mice is demonstrated and a novel polysynaptic circuit within the hypothalamus by which the central circadian clock influences neurons that regulate attack behavior is revealed.
Journal ArticleDOI
Reciprocal Control of Drinking Behavior by Median Preoptic Neurons in Mice.
TL;DR: It is demonstrated that glutamate and GABA neurons in the MnPO/OVLT reciprocally regulate water consumption, highlighting a heretofore unappreciated role of GABAergic MnPO neurons in thirst regulation.
Journal ArticleDOI
The Brazilian Peritoneal Dialysis Multicenter Study (BRAZPD) : characterization of the cohort.
Natália Maria da Silva Fernandes,Marcus Gomes Bastos,H.V. Cassi,Natalia L. S. Machado,J.A. Ribeiro,Gilberto de Andrade Martins,O. Mourao,Kleyton de Andrade Bastos,S.R. Ferreira Filho,V.M. Lemos,M. Abdo,M.T.I. Vannuchi,A. Mocelin,S.L. Bettoni,R.V. Valenzuela,M.M. Lima,Sérgio Wyton Lima Pinto,Miguel C. Riella,Abdul Rashid Qureshi,J.C. Divino Filho,Roberto Pecoits-Filho +20 more
TL;DR: The initial results of this first Brazilian PD registry provide a unique opportunity to develop future clinical studies addressing specific PD questions in the Brazilian reality and context.
Journal ArticleDOI
Oxidative stress causes hypertension and activation of nuclear factor-κB after high-fructose and salt treatments.
Waleska Claudia Amaral Dornas,Waleska Claudia Amaral Dornas,Leonardo Máximo Cardoso,Maísa Silva,Natalia L. S. Machado,Deoclécio Alves Chianca-Jr,Andréia Carvalho Alzamora,Wanderson Geraldo de Lima,Vincent Lagente,Marcelo Eustáquio Silva +9 more
TL;DR: The data suggested a possible role of oxygen radicals and ROS-induced activation of NF-κB in the fructose- and salt-induced hypertension associated with the progression of the renal disease.
Journal ArticleDOI
A Glutamatergic Hypothalamomedullary Circuit Mediates Thermogenesis, but Not Heat Conservation, during Stress-Induced Hyperthermia.
Natalia L. S. Machado,Natalia L. S. Machado,Stephen B. G. Abbott,Stephen B. G. Abbott,Jon M. Resch,Lin Zhu,Elda Arrigoni,Bradford B. Lowell,Patrick M. Fuller,Marco Antônio Peliky Fontes,Clifford B. Saper +10 more
TL;DR: The dissociation of the DHAVglut2 thermogenic pathway from the thermoregulatory vasoconstriction (heat-conserving) pathway may explain stress flushing (skin vasodilation but a feeling of being too hot) during stressful times.