Natasha Shinsky

TL;DR: The hypothesis that alpha-Syn is an essential presynaptic, activity-dependent negative regulator of DA neurotransmission is supported.

TL;DR: In this article, the authors demonstrate that neurotrophin-3 (NT-3), a member of the nerve growth factor family of neurotrophic factors, restored to normal levels the reduced H-reflex-related sensory nerve conduction velocity induced by cisplatin in rats.

TL;DR: It is demonstrated that intrahippocampal infusion of an EphA antagonist immunoadhesin leads to impaired performance in two behavioral paradigms, T-maze spontaneous alternation and context-dependent fear conditioning, sensitive to hippocampal function, whereas activation of Eph a by infusion of a agonist immunoad Heightsin results in enhanced performance on these tasks.

TL;DR: It is reported that transgenic mice with reduced levels of IGF-I show a decrease in motor and sensory nerve conduction velocities in vivo, and replacement therapy with exogenous recombinant hIGF-I restores both motor and Sensory nerve Conduction Velocities.

TL;DR: Results implicate REK7/EphA5 in the regulation of synaptic plasticity in the mature hippocampus and suggest that REK5 activation is recruited in the LTP induced by tetanization.