Robert Gerlai

TL;DR: The present article will demonstrate that the phenotypical abnormalities attributed to the null mutation in several molecular neurobiological studies could simply result from the effects of background genes.

TL;DR: A detailed catalog of zebrafish behaviors that covers both larval and adult models is developed, representing a beginning of creating a more comprehensive ethogram ofZebrafish behavior, which will improve interpretation of published findings, foster cross-species behavioral modeling, and encourage new groups to apply zebra fish neurobehavioral paradigms in their research.

TL;DR: It is argued that zebrafish models of complex brain disorders and drug-induced conditions are a rapidly emerging critical field in translational neuroscience and pharmacology research.

TL;DR: Basic behavioral tests to investigate the acute effects of alcohol on zebra fish and the strategy for generating and screening mutants will be useful for the genetic and biological analysis of acute and chronic drug effects as well as addiction.

TL;DR: Long-term potentiation (LTP) in mGluR5 mutants was significantly reduced in the NMDA receptor (NMDAR)-dependent pathways such as the CA1 region and dentate gyrus of the hippocampus, whereas LTP remained intact in the mossy fiber synapses on the CA3 region, an NMDAR-independent pathway.