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Nathalie Van Den Berge
Researcher at Aarhus University Hospital
Publications - 12
Citations - 568
Nathalie Van Den Berge is an academic researcher from Aarhus University Hospital. The author has contributed to research in topics: Parkinson's disease & Medicine. The author has an hindex of 4, co-authored 7 publications receiving 215 citations. Previous affiliations of Nathalie Van Den Berge include Aarhus University.
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Journal ArticleDOI
Evidence for bidirectional and trans-synaptic parasympathetic and sympathetic propagation of alpha-synuclein in rats.
Nathalie Van Den Berge,Nathalie Van Den Berge,Nelson Ferreira,Hjalte Gram,Trine Werenberg Mikkelsen,Aage Kristian Olsen Alstrup,Aage Kristian Olsen Alstrup,Nicolas Casadei,Pai Tsung-Pin,Olaf Riess,Jens R. Nyengaard,Gültekin Tamgüney,Gültekin Tamgüney,Poul Henning Jensen,Per Borghammer,Per Borghammer +15 more
TL;DR: The BAC rat model could be very valuable for detailed mechanistic studies of the dual-hit hypothesis, and for studies of disease modifying therapies targeting early pathology in the gastrointestinal tract, by performing immunohistochemistry at early time points post-injection.
Journal ArticleDOI
Brain-First versus Gut-First Parkinson's Disease: A Hypothesis.
TL;DR: It is hypothesized that PD can be divided into a PNS-first and a CNS-first subtype, which is tightly associated with REM sleep behavior disorder (RBD) during the prodromal phase and is characterized by marked autonomic damage before involvement of the dopaminergic system.
Journal ArticleDOI
Ageing promotes pathological alpha-synuclein propagation and autonomic dysfunction in wild-type rats.
Nathalie Van Den Berge,Nathalie Van Den Berge,Nelson Ferreira,Trine Werenberg Mikkelsen,Aage Kristian Olsen Alstrup,Aage Kristian Olsen Alstrup,Gültekin Tamgüney,Gültekin Tamgüney,Páll Karlsson,Astrid Juhl Terkelsen,Astrid Juhl Terkelsen,Jens R. Nyengaard,Poul Henning Jensen,Per Borghammer,Per Borghammer +14 more
TL;DR: In this paper, the authors investigated whether propagation of misfolded alpha-synuclein pathology from the gut to the brain is more efficient in old versus young wild-type rats.
Journal ArticleDOI
Neuropathological evidence of body-first vs. brain-first Lewy body disease.
Per Borghammer,Jacob Horsager,Katrine B. Andersen,Nathalie Van Den Berge,Anna Raunio,Shigeo Murayama,Laura Parkkinen,Liisa Myllykangas +7 more
TL;DR: In this paper, the authors explore the possibility that clinical body-first and brain-first subtypes are equivalent to the caudo-rostral and amygdala-centered patterns of Lewy pathology seen at post mortem.
Journal ArticleDOI
Asymmetric Dopaminergic Dysfunction in Brain-First versus Body-First Parkinson's Disease Subtypes.
Karoline Knudsen,Tatyana D. Fedorova,Jacob Horsager,Katrine B. Andersen,Casper Skjærbæk,Daniela Berg,Eva Schaeffer,David J. Brooks,Nicola Pavese,Nathalie Van Den Berge,Per Borghammer +10 more
TL;DR: In this article, Wu et al. analyzed striatal asymmetry in [18F]FDOPA PET and [123I]FP-CIT DaT SPECT data from iRBD patients, de novo PD patients with RBD (PD +RBD) and de nono PD patients without RBD(PD - RBD).