N
Nicole Ryan
Researcher at University of Pennsylvania
Publications - 12
Citations - 630
Nicole Ryan is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Hypsarrhythmia & Epilepsy. The author has an hindex of 9, co-authored 12 publications receiving 477 citations. Previous affiliations of Nicole Ryan include Boston Children's Hospital & Hospital of the University of Pennsylvania.
Papers
More filters
Journal ArticleDOI
Response to treatment in a prospective national infantile spasms cohort
Kelly G. Knupp,Jason Coryell,Katherine C. Nickels,Nicole Ryan,Erin C. Leister,Tobias Loddenkemper,Zachary M. Grinspan,Adam L. Hartman,Eric H. Kossoff,William D. Gaillard,John R. Mytinger,Sucheta M. Joshi,Renée A. Shellhaas,Joseph Sullivan,Dennis J. Dlugos,Lorie Hamikawa,Anne T. Berg,John Millichap,Douglas R. Nordli,Elaine C. Wirrell +19 more
TL;DR: This study evaluates early and sustained response to initial treatments and addresses both clinical remission and electrographic resolution of hypsarrhythmia in infants with infantile spasms.
Journal ArticleDOI
Early-Life Epilepsies and the Emerging Role of Genetic Testing.
Anne T. Berg,Anne T. Berg,Jason Coryell,Russell P. Saneto,Zachary M. Grinspan,Zachary M. Grinspan,John J. Alexander,Mariana Kekis,Joseph Sullivan,Elaine C. Wirrell,Renée A. Shellhaas,John R. Mytinger,John R. Mytinger,William D. Gaillard,Eric H. Kossoff,Ignacio Valencia,Kelly G. Knupp,Courtney J. Wusthoff,Cynthia Keator,William B. Dobyns,Nicole Ryan,Tobias Loddenkemper,Catherine J. Chu,Edward J. Novotny,Edward J. Novotny,Sookyong Koh +25 more
TL;DR: Thorough genetic investigation emphasizing sequencing tests should be incorporated into the initial evaluation of newly presenting early-life epilepsies and not just reserved for those with severe presentations and poor outcomes.
Journal ArticleDOI
Hypsarrhythmia assessment exhibits poor interrater reliability: a threat to clinical trial validity.
Shaun A. Hussain,Grace Kwong,John Millichap,John R. Mytinger,Nicole Ryan,Joyce H. Matsumoto,Joyce Y. Wu,Jason T. Lerner,Raman Sankar +8 more
TL;DR: This work sought to test the IRR of hypsarrhythmia assessment in a systematic fashion, and found that assessments of voltage and disorganization are fairly subjective, and thus quite challenging in borderline cases.
Journal ArticleDOI
Anti–N-methyl-D-aspartate Receptor-Mediated Encephalitis in Infants and Toddlers: Case Report and Review of the Literature
Ethan M. Goldberg,Ethan M. Goldberg,Maarten J. Titulaer,Maarten J. Titulaer,Peter de Blank,Angela J. Sievert,Nicole Ryan,Nicole Ryan +7 more
TL;DR: Anti-N-methyl-D-aspartate receptor encephalitis is relatively common among infants and toddlers and often presents with a pattern of defining characteristics in this age group, particularly the absence of associated tumor.
Journal ArticleDOI
Response to second treatment after initial failed treatment in a multicenter prospective infantile spasms cohort.
Kelly G. Knupp,Erin C. Leister,Jason Coryell,Katherine C. Nickels,Nicole Ryan,Elizabeth Juarez-Colunga,William D. Gaillard,John R. Mytinger,Anne T. Berg,John Millichap,Douglas R. Nordli,Sucheta M. Joshi,Renée A. Shellhaas,Tobias Loddenkemper,Dennis J. Dlugos,Elaine C. Wirrell,Joseph Sullivan,Adam L. Hartman,Eric H. Kossoff,Zachary M. Grinspan,Lorie Hamikawa +20 more
TL;DR: This work evaluated response to second treatment for IS in children in whom the initial therapy failed to produce both clinical remission and electrographic resolution of hypsarhythmia and whether time to treatment was related to outcome.