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Nobuhiro Miyamura
Researcher at Kumamoto University
Publications - 32
Citations - 1181
Nobuhiro Miyamura is an academic researcher from Kumamoto University. The author has contributed to research in topics: Insulin & Diabetes mellitus. The author has an hindex of 19, co-authored 32 publications receiving 1117 citations.
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Journal ArticleDOI
Evaluation of urinary 8-hydroxydeoxy-guanosine as a novel biomarker of macrovascular complications in type 2 diabetes
Takeshi Nishikawa,Takayuki Sasahara,Shinsuke Kiritoshi,Kazuhiro Sonoda,Takahumi Senokuchi,Tomoko Matsuo,Daisuke Kukidome,Nakayasu Wake,Takeshi Matsumura,Nobuhiro Miyamura,Michiharu Sakakida,Hideki Kishikawa,Eiichi Araki +12 more
TL;DR: Hyperglycemia independently increases 8-OHdG in patients with type 2 diabetes, and this biomarker is a useful biomarker of not only microvascular but also macrovascular complications in Patients withType 2 diabetes.
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Effect on insulin sensitivity of angiotensin converting enzyme inhibitors with or without a sulphydryl group: Bradykinin may improve insulin resistance in dogs and humans
M. Uehara,Hideki Kishikawa,S. Isami,K. Kisanuki,Yasuo Ohkubo,Nobuhiro Miyamura,Takao Miyata,Tomohiko Yano,Motoaki Shichiri +8 more
TL;DR: It is concluded that ACE inhibitors with a sulphydryl group have more potent action on the improvement in insulin sensitivity than those without a sulphytol group.
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Bradykinin enhances GLUT4 translocation through the increase of insulin receptor tyrosine kinase in primary adipocytes: evidence that bradykinin stimulates the insulin signalling pathway.
S. Isami,Hideki Kishikawa,Eiichi Araki,M. Uehara,Kengo Kaneko,Tetsuya Shirotani,Mikio Todaka,S. Ura,S. Motoyoshi,K. Matsumoto,Nobuhiro Miyamura,Motoaki Shichiri +11 more
TL;DR: It is concluded that bradykinin could potentiate insulin induced glucose uptake through GLUT4 translocation by upregulating the insulin receptor tyrosine kinase activity which stimulates phosphorylation of IRS-1, followed by GLUT 4 translocation.
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Inherited adrenocorticotropin-independent macronodular adrenal hyperplasia with abnormal cortisol secretion by vasopressin and catecholamines: detection of the aberrant hormone receptors on adrenal gland.
Nobuhiro Miyamura,Tetsuya Taguchi,Yusuke Murata,Kayo Taketa,Shinsuke Iwashita,Kazuya Matsumoto,Takeshi Nishikawa,Tetsushi Toyonaga,Michiharu Sakakida,Eiichi Araki +9 more
TL;DR: An intervention could be tried to prevent the development of overt Cushing’s syndrome by suppression of the possible endogenous ligands or by blockade of the receptors that may be aberrantly expressed in his adrenal glands.
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Diagnosis and treatment of adrenal insufficiency including adrenal crisis: a Japan Endocrine Society clinical practice guideline [Opinion]
Toshihiko Yanase,Toshihiro Tajima,Takuyuki Katabami,Yasumasa Iwasaki,Yusuke Tanahashi,Akira Sugawara,Tomonobu Hasegawa,Tomoatsu Mune,Yutaka Oki,Yuichi Nakagawa,Nobuhiro Miyamura,Chikara Shimizu,Michio Otsuki,Masatoshi Nomura,Yuko Akehi,Makito Tanabe,Soji Kasayama +16 more
TL;DR: This clinical practice guideline of the diagnosis and treatment of adrenal insufficiency (AI) including adrenal crisis was developed by a committee including all authors, and was reviewed by a subcommittee of the Japan Endocrine Society.