N
Norbert Weiler
Researcher at University of Kiel
Publications - 118
Citations - 6634
Norbert Weiler is an academic researcher from University of Kiel. The author has contributed to research in topics: Breathing & Intensive care. The author has an hindex of 30, co-authored 110 publications receiving 5997 citations. Previous affiliations of Norbert Weiler include Keil.
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Journal ArticleDOI
Intensive insulin therapy and pentastarch resuscitation in severe sepsis.
Frank M. Brunkhorst,Christoph Engel,Frank Bloos,Andreas Meier-Hellmann,Max Ragaller,Norbert Weiler,Onnen Moerer,Matthias Gruendling,Michael Oppert,Stefan Grond,Derk Olthoff,Ulrich Jaschinski,Stefan John,Rolf Rossaint,Tobias Welte,Martin Schaefer,Peter M. Kern,Evelyn Kuhnt,Michael Kiehntopf,Christiane S. Hartog,Charles Natanson,Markus Loeffler,Konrad Reinhart +22 more
TL;DR: The use of intensive insulin therapy placed critically ill patients with sepsis at increased risk for serious adverse events related to hypoglycemia and HES was harmful, and its toxicity increased with accumulating doses.
Journal ArticleDOI
Epidemiology of sepsis in Germany: results from a national prospective multicenter study
Christoph Engel,Frank M. Brunkhorst,Hans-Georg Bone,Reinhard Richard Brunkhorst,Herwig Gerlach,Stefan Grond,Matthias Gruendling,Guenter Huhle,Ulrich Jaschinski,Stefan John,Konstantin Mayer,Michael Oppert,Derk Olthoff,Michael Quintel,Max Ragaller,Rolf Rossaint,Frank Stüber,Norbert Weiler,Tobias Welte,Holger Bogatsch,Christiane S. Hartog,Markus Loeffler,Konrad Reinhart +22 more
TL;DR: The expected number of newly diagnosed cases with severe sepsis in Germany amounts to 76–110 per 100,000 adult inhabitants and future epidemiological studies should use standardized study methodologies with respect to sepsi definitions, hospital size, and daily and monthly variability.
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The effect of a novel extracorporeal cytokine hemoadsorption device on IL-6 elimination in septic patients: A randomized controlled trial
Dirk Schädler,Christine Pausch,Daniel Heise,Andreas Meier-Hellmann,Jörg Brederlau,Norbert Weiler,Gernot Marx,Christian Putensen,Claudia Spies,Achim Jörres,Michael Quintel,Christoph Engel,John A. Kellum,Martin K. Kuhlmann +13 more
TL;DR: In this patient population with predominantly septic shock and multiple organ failure, hemoadsorption removed IL-6 but this did not lead to lower plasma IL- 6-levels.
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Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis The HYPRESS Randomized Clinical Trial
Didier Keh,Evelyn Trips,Gernot Marx,Stefan Wirtz,Emad Abduljawwad,Sven Bercker,Holger Bogatsch,Josef Briegel,Christoph Engel,Herwig Gerlach,Anton Goldmann,Sven-Olaf Kuhn,Lars Hüter,Andreas Meier-Hellmann,Axel Nierhaus,Stefan Kluge,Josefa Lehmke,Markus Loeffler,Michael Oppert,Kerstin Resener,Dirk Schädler,Tobias Schuerholz,Philipp Simon,Norbert Weiler,Andreas Weyland,Konrad Reinhart,Frank M. Brunkhorst +26 more
TL;DR: Among adults with severe sepsis not in septic shock, use of hydrocortisone compared with placebo did not reduce the risk of septicshock within 14 days, and these findings do not support the use ofHydroc Cortisone in these patients.
Journal ArticleDOI
Close to recommended caloric and protein intake by enteral nutrition is associated with better clinical outcome of critically ill septic patients: secondary analysis of a large international nutrition database
TL;DR: In critically ill septic patients, a calorie and protein delivery closer to recommended amounts by EN in the early phase of ICU stay was associated with a more favorable outcome.