O
Onnen Moerer
Researcher at University of Göttingen
Publications - 164
Citations - 7607
Onnen Moerer is an academic researcher from University of Göttingen. The author has contributed to research in topics: Medicine & Intensive care unit. The author has an hindex of 35, co-authored 134 publications receiving 6395 citations. Previous affiliations of Onnen Moerer include University of Toronto.
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Journal ArticleDOI
Intensive insulin therapy and pentastarch resuscitation in severe sepsis.
Frank M. Brunkhorst,Christoph Engel,Frank Bloos,Andreas Meier-Hellmann,Max Ragaller,Norbert Weiler,Onnen Moerer,Matthias Gruendling,Michael Oppert,Stefan Grond,Derk Olthoff,Ulrich Jaschinski,Stefan John,Rolf Rossaint,Tobias Welte,Martin Schaefer,Peter M. Kern,Evelyn Kuhnt,Michael Kiehntopf,Christiane S. Hartog,Charles Natanson,Markus Loeffler,Konrad Reinhart +22 more
TL;DR: The use of intensive insulin therapy placed critically ill patients with sepsis at increased risk for serious adverse events related to hypoglycemia and HES was harmful, and its toxicity increased with accumulating doses.
Journal ArticleDOI
Ventilator-related causes of lung injury: the mechanical power.
Luciano Gattinoni,Tommaso Tonetti,Massimo Cressoni,P. Cadringher,Peter Herrmann,Onnen Moerer,Alessandro Protti,Miriam Gotti,Chiara Chiurazzi,Eleonora Carlesso,Davide Chiumello,Michael Quintel +11 more
TL;DR: The mechanical power equation may help estimate the contribution of the different ventilator-related causes of lung injury and of their variations.
Journal ArticleDOI
Digital Droplet PCR for Rapid Quantification of Donor DNA in the Circulation of Transplant Recipients as a Potential Universal Biomarker of Graft Injury
Julia Beck,Sarah Bierau,Stefan Balzer,Reiner Andag,Philipp Kanzow,Jessica Schmitz,Jochen Gaedcke,Onnen Moerer,Jan E. Slotta,Philip D. Walson,Otto Kollmar,Michael Oellerich,Ekkehard Schütz +12 more
TL;DR: A novel, cost-effective, rapid technique was developed to quantify GcfDNA in transplant recipients and embodies a promising, potentially universal biomarker for early detection of rejection, which could enable more effective therapeutic interventions.
Journal ArticleDOI
Effect of Sodium Selenite Administration and Procalcitonin-Guided Therapy on Mortality in Patients With Severe Sepsis or Septic Shock: A Randomized Clinical Trial.
Frank Bloos,Evelyn Trips,Axel Nierhaus,Josef Briegel,Daren K. Heyland,Ulrich Jaschinski,Onnen Moerer,Andreas Weyland,Gernot Marx,Matthias Gründling,Stefan Kluge,Ines Kaufmann,Klaus Ott,Michael Quintel,Florian Jelschen,Patrick Meybohm,Sibylle Rademacher,Andreas Meier-Hellmann,Stefan Utzolino,Udo Kaisers,Christian Putensen,Gunnar Elke,Maximilian Ragaller,Herwig Gerlach,Katrin Ludewig,Michael Kiehntopf,Holger Bogatsch,Christoph Engel,Frank M. Brunkhorst,Markus Loeffler,Konrad Reinhart +30 more
TL;DR: Neither high-dose intravenous administration of sodium selenite nor anti-infectious therapy guided by a procalcitonin algorithm was associated with an improved outcome in patients with severe sepsis.
Journal ArticleDOI
A Novel Extracorporeal CO2 Removal System: Results of a Pilot Study of Hypercapnic Respiratory Failure in Patients With COPD
Nausherwan K. Burki,Raj Kumar Mani,Felix J.F. Herth,Werner Schmidt,Helmut Teschler,Frank Bonin,Heinrich D. Becker,Winfried Randerath,Sven Stieglitz,Lars Hagmeyer,Christina Priegnitz,Michael Pfeifer,Stefan Blaas,Christian Putensen,Nils Theuerkauf,Michael Quintel,Onnen Moerer +16 more
TL;DR: This single-catheter, low-flow ECCO2R system provided clinically useful levels of CO2 removal in these patients with COPD and appears to be a potentially valuable additional modality for the treatment of hypercapnic respiratory failure.