Noriko K. Takahashi

TL;DR: Investigation of many newly identified gene products, including the 70 putative virulence factors, will greatly improve the understanding of the biology of staphylococci and the processes of infectious diseases caused by S aureus.

TL;DR: The demonstrated repair of a double-stranded DNA gap through gene conversion by a homologous DNA sequence in Escherichia coli can explain plasmid recombination in the absence of an artificial double-Stranded break reported in a companion study by Yamamoto et al.

TL;DR: It is demonstrated that a double-stranded gap in DNA is repaired by a gene conversion mechanism in an Escherichia coli recBC sbcA23 strain, as predicted by the ds break repair models for homologous recombination and concluded that both ExoVIII and RecT are essential for ds gap repair.

TL;DR: It is concluded that the RecBCD, Rec BCD-, and RecF pathways cannot promote conservative double-strand break repair as the RecE and lambda Red pathways can.

TL;DR: Evidence is presented that the mode of homologous recombination is nonconservative in an Escherichia coli strain with an active RecF pathway (a recBC sbcBC mutant) and plasmid substrates that enable us to recover both recombination products.