O
Oi Wah Liew
Researcher at National University of Singapore
Publications - 93
Citations - 1498
Oi Wah Liew is an academic researcher from National University of Singapore. The author has contributed to research in topics: Drop (liquid) & Contact angle. The author has an hindex of 19, co-authored 82 publications receiving 1190 citations. Previous affiliations of Oi Wah Liew include University Health System.
Papers
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Journal ArticleDOI
Growth differentiation factor 15 in heart failure with preserved vs. reduced ejection fraction.
Michelle Chan,Rajalakshmi Santhanakrishnan,Jenny P.C. Chong,Zhaojin Chen,Bee Choo Tai,Oi Wah Liew,Tze Pin Ng,Lieng H. Ling,David Sim,Kui Toh G. Leong,Poh Shuan Daniel Yeo,Hean Yee Ong,Fazlur Jaufeerally,Raymond Ching-Chiew Wong,Ping Chai,Adrian F. Low,Arthur Mark Richards,Carolyn S.P. Lam,Carolyn S.P. Lam +18 more
TL;DR: This study aimed to study the clinical correlates and prognostic significance of plasma GDF15 in heart failure with preserved ejection fraction compared with N‐terminal pro‐brain natriuretic peptide (NT‐proBNP), an indicator of haemodynamic wall stress.
Journal ArticleDOI
Overview of MicroRNAs in Cardiac Hypertrophy, Fibrosis, and Apoptosis
Juan Wang,Oi Wah Liew,Arthur Mark Richards,Arthur Mark Richards,Yei Tsung Chen,Yei Tsung Chen +5 more
TL;DR: Comparison across 86 studies identified several candidate miRNAs that might be of particular importance in the ontogenesis of cardiovascular diseases as they modulate the expression of clusters of target genes involved in the progression of multiple adverse cardiovascular events.
Journal ArticleDOI
MicroRNA and Heart Failure
Lee Lee Wong,Juan Wang,Oi Wah Liew,Arthur Mark Richards,Arthur Mark Richards,Arthur Mark Richards,Yei Tsung Chen +6 more
TL;DR: An overview of the role of mi RNAs in the cardiovascular system is provided and several HF-related miRNAs reported from selected cohorts are highlighted and their putative roles in neurohormonal signaling are reviewed.
Journal ArticleDOI
Intracellular Adenosine Triphosphate Deprivation through Lanthanide-Doped Nanoparticles.
Jing Tian,Jing Tian,Xiao Zeng,Xiaoji Xie,Sanyang Han,Oi Wah Liew,Yei Tsung Chen,Lianhui Wang,Xiaogang Liu,Xiaogang Liu +9 more
TL;DR: It is found that ligand-free lanthanide-doped nanoparticles induce intracellular ATP deprivation of HeLa cells, resulting in a significant decrease in cell viability after exposure for 7 days, and attribute the particle-induced cell death to two distinct cell death pathways, autophagy and apoptosis.
Journal ArticleDOI
Discovery of Novel Small Molecule Inhibitors of Dengue Viral NS2B-NS3 Protease Using Virtual Screening and Scaffold Hopping
Jing Deng,Ning Li,Hongchuan Liu,Zhili Zuo,Oi Wah Liew,Weijun Xu,Gang Chen,Xiankun Tong,Wei Tang,Jin Zhu,Jianping Zuo,Hualiang Jiang,Hualiang Jiang,Cai-Guang Yang,Jian Li,Weiliang Zhu +15 more
TL;DR: 17 new compounds were discovered as NS2B-NS3 protease inhibitors with IC(50) values of 7.46 ± 1.15 to 48.59 ± 3.46 μM, and 8 compounds belonging to two different scaffolds are active to some extent against DENV based on luciferase reporter replicon-based assays.