O
Olga Kelemen
Researcher at University of Kentucky
Publications - 8
Citations - 558
Olga Kelemen is an academic researcher from University of Kentucky. The author has contributed to research in topics: Internal medicine & Medicine. The author has an hindex of 3, co-authored 4 publications receiving 460 citations. Previous affiliations of Olga Kelemen include University of California, San Diego.
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Journal ArticleDOI
ReviewFunction of alternative splicing
Olga Kelemen,Paolo Convertini,Zhaiyi Zhang,Yuan Wen,Manli Shen,Marina Falaleeva,Stefan Stamm +6 more
TL;DR: The overall function of alternative splicing is to increase the diversity of mRNAs expressed from the genome as mentioned in this paper, which can have profound functional effects, such as increasing cell proliferation, cell survival and properties of the nervous system.
Journal ArticleDOI
C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1
Chiranthani Sumanasekera,Olga Kelemen,Monique Beullens,Brandon E. Aubol,Joseph A. Adams,Manjula Sunkara,Andrew J. Morris,Mathieu Bollen,Athena Andreadis,Stefan Stamm +9 more
TL;DR: The results indicate that lipids can influence pre-mRNA processing by regulating the phosphorylation status of specific regulatory factors, which is mediated by protein phosphatase activity.
Journal ArticleDOI
Synthesis and Characterization of Pseudocantharidins, Novel Phosphatase Modulators That Promote the Inclusion of Exon 7 into the SMN (Survival of Motoneuron) pre-mRNA
Zhaiyi Zhang,Olga Kelemen,Maria A. van Santen,Sharon Yelton,Alison E. Wendlandt,Vitaliy M. Sviripa,Mathieu Bollen,Monique Beullens,Henning Urlaub,Reinhard Lührmann,David S. Watt,Stefan Stamm +11 more
TL;DR: The data show that subtle changes in similar compounds can turn a phosphatase inhibitor into an activator, and chemically related compounds influence alternative splicing by distinct mechanisms.
Proceedings ArticleDOI
2022-RA-1048-ESGO Circulating HPV cell-free DNA in cervical cancer
Suzana Doneda Mittelstadt,Christopher Schroeder,Olga Kelemen,T Engler,Jakob Admard,Axel Gschwind,Andre Koch,S. Wörz,E Oberlechner,S Hoffmann,Jürgen Andress,Felix Neis,Bernhard K. Krämer,Irina Bonzheim,Annette Staebler,Frank Stubenrauch,Thomas Iftner,Stephan Ossowski,Stefan Kommoss +18 more
TL;DR: Lee et al. as discussed by the authors investigated prognostic factors of neuroendocrine carcinoma of the cervix and compared survival outcomes according to the treatment methods, and found that the fall in colposcopy clinic referral can be explained by the disruptions from the COVID 19 pandemic as cervical screening invitations reduced during this time.
Proceedings ArticleDOI
O032/#771 Circulating HPV cell-free DNA in cervical cancer
Suzana Doneda Mittelstadt,Christopher Schroeder,Olga Kelemen,Admard Jakob,Axel Gschwind,Andre Koch,S. Wörz,E Oberlechner,S Hoffmann,T Engler,Jürgen Andress,Felix Neis,Bernhard K. Krämer,Irina Bonzheim,Annette Staebler,Frank Stubenrauch,Stephan Ossowski,Stefan Kommoss +17 more
TL;DR: In this article , the potential use of human papillomavirus (HPV) cell-free circulating DNA (cfDNA) in plasma samples of patients with cervical cancer was investigated.