T
Thomas Iftner
Researcher at University of Tübingen
Publications - 218
Citations - 10668
Thomas Iftner is an academic researcher from University of Tübingen. The author has contributed to research in topics: Cervical cancer & Population. The author has an hindex of 50, co-authored 199 publications receiving 9653 citations. Previous affiliations of Thomas Iftner include University of Erlangen-Nuremberg & University of Copenhagen.
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Journal ArticleDOI
Overview of the European and North American studies on HPV testing in primary cervical cancer screening.
Jack Cuzick,Christine Clavel,Karl Ulrich Petry,Chris J.L.M. Meijer,Heike Hoyer,Sam Ratnam,Anne Szarewski,Philippe Birembaut,Shalini L Kulasingam,Peter Sasieni,Thomas Iftner +10 more
TL;DR: The results support the use of HPV testing as the sole primary screening test, with cytology reserved for women who test HPV positive, with large demonstration projects needed to fully evaluate this strategy.
Journal ArticleDOI
Long term predictive values of cytology and human papillomavirus testing in cervical cancer screening: joint European cohort study
Joakim Dillner,Matejka Rebolj,Philippe Birembaut,Karl Ulrich Petry,Anne Szarewski,Christian Munk,Silvia de Sanjosé,Pontus Naucler,Belen Lloveras,Susanne K. Kjaer,Jack Cuzick,Marjolein van Ballegooijen,Christine Clavel,Thomas Iftner +13 more
TL;DR: A consistently low six year cumulative incidence rate of CIN3+ among women negative for HPV suggests that cervical screening strategies in which women are screened for HPV every six years are safe and effective.
Journal ArticleDOI
Long-term Absolute Risk of Cervical Intraepithelial Neoplasia Grade 3 or Worse Following Human Papillomavirus Infection: Role of Persistence
TL;DR: HP16, HPV18, HPV31, and HPV33 infection and especially HPV16 persistence were associated with high absolute risks for progression to high-grade cervical lesions and the results indicate the potential value of genotyping in cervical cancer screening.
Journal ArticleDOI
Comprehensive control of human papillomavirus infections and related diseases.
F. Xavier Bosch,Thomas R. Broker,David Forman,Anna-Barbara Moscicki,Maura L. Gillison,John Doorbar,Peter L. Stern,Margaret Stanley,Marc Arbyn,Mario Poljak,Jack Cuzick,Philip E. Castle,John T. Schiller,Lauri E. Markowitz,William A. Fisher,Karen Canfell,Lynette Denny,Eduardo L. Franco,Marc Steben,Mark A. Kane,Mark Schiffman,Chris J.L.M. Meijer,Rengaswamy Sankaranarayanan,Xavier Castellsagué,Jane J. Kim,Maria Brotons,Laia Alemany,Ginesa Albero,Mireia Diaz,Silvia de Sanjosé,Ahti Anttila,Lawrence Banks,Christine Bergeron,Jerome L. Belinson,Johannes Berkhof,Ignacio G. Bravo,Freddie Bray,Julia M.L. Brotherton,Laia Bruni,Ann N. Burchell,Anil K. Chaturvedi,Harrell W. Chesson,Myriam Chevarie-Davis,Heather Cubie,Shelley L. Deeks,Catherine de Martel,Joakim Dillner,Mark H. Einstein,Jacques Ferlay,Alison Nina Fiander,Silvia Franceschi,Suzanne M. Garland,Anna R. Giuliano,Marc T. Goodman,Patti E. Gravitt,Ian N. Hampson,Isabelle Heard,Thomas Iftner,Sandra D. Isidean,Christina Jensen,Jose Jeronimo,Walter Kinney,Henry C Kitchener,Susanne K. Kjaer,Boŝtjan J. Kocjan,George Koliopoulos,Shalini L Kulasingam,Charles J.N. Lacey,D. Scott LaMontagne,Eduardo Lazcano-Ponce,Attila T. Lorincz,Joannie Lortet-Tieulent,Pontus Naucler,Gina Ogilvie,Joel M. Palefsky,Julian Peto,Ligia A. Pinto,Martyn Plummer,You-Lin Qiao,Wim Quint,Guglielmo Ronco,Steve Schwartz,Beatriz Serrano,Jennifer S. Smith,Peter J.F. Snijders,Isabelle Soerjomataram,Bettie M. Steinberg,Mark H. Stoler,Anne Szarewski,Connie Trimble,Vivien Tsu,Pierre Van Damme,Sjoerd H. van der Burg,Andrea Vicari,Jérôme Vignat,Magnus von Knebel Doeberitz,Alex Vorsters,Susan A. Wang,Scott Wittet +98 more
TL;DR: There must be ongoing efforts including international advocacy to achieve widespread-optimally universal-implementation of HPV prevention strategies in both developed and developing countries.
Journal ArticleDOI
TLR9 expression and function is abolished by the cervical cancer-associated human papillomavirus type 16.
Uzma Hasan,Elizabeth E.M. Bates,Fumihiko Takeshita,Alexandra Biliato,Rosita Accardi,Véronique Bouvard,Mariam Mansour,Isabelle Vincent,Lutz Gissmann,Thomas Iftner,Mario Sideri,Frank Stubenrauch,Massimo Tommasino +12 more
TL;DR: A novel mechanism used by HPV16 to suppress the host immune response by deregulating the TLR9 transcript is revealed, providing evidence that abolishing innate responses may be a crucial step involved in the carcinogenic events mediated by HPVs.