Olivia Bermingham-McDonogh

TL;DR: Alternative splicing of the messenger RNA generates an array of putative membrane-attached, intracellular and secreted signalling proteins, at least some of which are expressed in the developing spinal cord and brain.

TL;DR: Three key epochs are defined in the transcriptome dynamics of human retina from fetal day (D) 52 to 136 to confirm the cellular basis of transcriptional changes and highlight the dramatic acceleration of development in the fovea compared with peripheral retina.

TL;DR: It is found that broad ectopic activation of Notch at very early developmental stages causes induction of prosensory markers throughout the entire otic epithelium, and this results support a model where activation of notch and propagation through lateral induction promote Prosensory character in specific regions of the developing otocyst.

TL;DR: The authors' single-cell RNA sequencing comparisons of fetal retina, retinal organoids, and retinospheres provide a resource for developing better in vitro models for retinal disease.

TL;DR: An analysis of the expression of Prox1, a homeodomain transcription factor, during mouse inner ear development with particular emphasis on the auditory system, found that the outer hair cells transiently expressprox1.