Olle Melander

TL;DR: Exposure to cholesterol and family history of MI more strongly predicts onset of MI at younger ages, suggesting that MI in younger subjects is preceded by a different risk factor pattern than MI presenting in older subjects.

TL;DR: The in vitro experiments support the view that these biomarkers could reflect activation of the extrinsic apoptotic pathway and were associated with increased incidence of CE in subjects from the general population.

TL;DR: This study used a multifaceted screening strategy that integrates bioinformatics, next-generation sequencing data, human genetic association data, and cellular models to identify additional functional NPPA-targeting miRNAs that could be targeted to raise ANP levels, which may have applications for the treatment of hypertension or heart failure.

TL;DR: Plasma concentration of C3 is a risk marker for incidence of diabetes and the results suggest that this association could, in part, be explained by pleiotropic effects related to the GCKR gene.

TL;DR: Both dietary assessment methods were able to capture dietary intake based on food groups with a similar precision and the ability to capture whole grain intake was weak for both methods and sexes, but the assessment of vegetable and fruit intake performed in a satisfactory manner for women in both methods.