J
J. Gustav Smith
Researcher at Lund University
Publications - 175
Citations - 10138
J. Gustav Smith is an academic researcher from Lund University. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 45, co-authored 149 publications receiving 7841 citations. Previous affiliations of J. Gustav Smith include Copenhagen University Hospital & University of Gothenburg.
Papers
More filters
Journal ArticleDOI
Genetic associations with valvular calcification and aortic stenosis.
George Thanassoulis,George Thanassoulis,Catherine Y. Campbell,David S. Owens,J. Gustav Smith,J. Gustav Smith,Albert V. Smith,Gina M. Peloso,Gina M. Peloso,Kathleen F. Kerr,Sonali Pechlivanis,Matthew J. Budoff,Tamara B. Harris,Rajeev Malhotra,Kevin D. O'Brien,Pia R. Kamstrup,Børge G. Nordestgaard,Anne Tybjærg-Hansen,Matthew A. Allison,Thor Aspelund,Michael H. Criqui,Susan R. Heckbert,Shih-Jen Hwang,Yongmei Liu,Marketa Sjögren,Jesper van der Pals,Hagen Kälsch,Thomas W. Mühleisen,Markus M. Nöthen,L. Adrienne Cupples,L. Adrienne Cupples,Muriel J. Caslake,Emanuele Di Angelantonio,John Danesh,Jerome I. Rotter,Sigurdur Sigurdsson,Quenna Wong,Raimund Erbel,Sekar Kathiresan,Sekar Kathiresan,Olle Melander,Vilmundur Gudnason,Christopher J. O'Donnell,Christopher J. O'Donnell,Wendy S. Post +44 more
TL;DR: Genetic variation in the LPA locus, mediated by Lp(a) levels, is associated with aortic-valve calcification across multiple ethnic groups and with incident clinical aorti stenosis.
Journal ArticleDOI
Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials
Jessica L. Mega,Nathan O. Stitziel,J. Gustav Smith,J. Gustav Smith,Daniel I. Chasman,Mark J. Caulfield,James J. Devlin,Francesco Nordio,Craig L. Hyde,Christopher P. Cannon,Frank M. Sacks,Neil Poulter,Peter S. Sever,Paul M. Ridker,Eugene Braunwald,Olle Melander,Sekar Kathiresan,Marc S. Sabatine +17 more
TL;DR: People with the highest burden of genetic risk derived the largest relative and absolute clinical benefit from statin therapy.
Journal ArticleDOI
Novel and Conventional Biomarkers for Prediction of Incident Cardiovascular Events in the Community
Olle Melander,Christopher Newton-Cheh,Christopher Newton-Cheh,Peter Almgren,Bo Hedblad,Göran Berglund,Gunnar Engström,Margaretha Persson,J. Gustav Smith,Martin Magnusson,Anders Christensson,Joachim Struck,Nils G. Morgenthaler,Andreas Bergmann,Michael J. Pencina,Thomas J. Wang +15 more
TL;DR: Evaluated biomarkers may be used to predict future cardiovascular events, but the gains over conventional risk factors are minimal and greater improvements were observed in analyses restricted to intermediate-risk individuals.
Journal ArticleDOI
Meta-analysis identifies six new susceptibility loci for atrial fibrillation
Patrick T. Ellinor,Kathryn L. Lunetta,Christine M. Albert,Christine M. Albert,Nicole L. Glazer,Marylyn D. Ritchie,Albert V. Smith,Dan E. Arking,Martina Müller-Nurasyid,Bouwe P. Krijthe,Steven A. Lubitz,Steven A. Lubitz,Joshua C. Bis,Mina K. Chung,Mina K. Chung,Marcus Dörr,Kouichi Ozaki,Jason D. Roberts,J. Gustav Smith,J. Gustav Smith,Arne Pfeufer,Moritz F. Sinner,Moritz F. Sinner,Moritz F. Sinner,Kurt Lohman,Jingzhong Ding,Nicholas L. Smith,Jonathan D. Smith,Jonathan D. Smith,Michiel Rienstra,Kenneth Rice,David R. Van Wagoner,David R. Van Wagoner,Jared W. Magnani,Reza Wakili,Sebastian Clauss,Jerome I. Rotter,Gerhard Steinbeck,Lenore J. Launer,Robert W. Davies,Matthew Borkovich,Tamara B. Harris,Honghuang Lin,Uwe Völker,Henry Völzke,David J. Milan,Albert Hofman,Eric Boerwinkle,Lin Y. Chen,Elsayed Z. Soliman,Benjamin F. Voight,Guo Li,Aravinda Chakravarti,Michiaki Kubo,Usha B. Tedrow,Usha B. Tedrow,Lynda M. Rose,Paul M. Ridker,Paul M. Ridker,David Conen,Tatsuhiko Tsunoda,Tetsushi Furukawa,Nona Sotoodehnia,Siyan Xu,Naoyuki Kamatani,Daniel Levy,Yusuke Nakamura,Babar Parvez,Saagar Mahida,Karen L. Furie,Jonathan Rosand,Raafia Muhammad,Bruce M. Psaty,Thomas Meitinger,Siegfried Perz,H-Erich Wichmann,Jacqueline C.M. Witteman,W. H. Linda Kao,Sekar Kathiresan,Sekar Kathiresan,Dan M. Roden,André G. Uitterlinden,Fernando Rivadeneira,Barbara McKnight,Marketa Sjögren,Anne B. Newman,Yongmei Liu,Michael H. Gollob,Olle Melander,Toshihiro Tanaka,Bruno H. Stricker,Stephan B. Felix,Alvaro Alonso,Dawood Darbar,John Barnard,Daniel I. Chasman,Daniel I. Chasman,Susan R. Heckbert,Susan R. Heckbert,Emelia J. Benjamin,Vilmundur Gudnason,Stefan Kääb +101 more
TL;DR: Six new atrial fibrillation susceptibility loci implicate candidate genes that encode transcription factors related to cardiopulmonary development, cardiac-expressed ion channels and cell signaling molecules that are associated with stroke, heart failure and death.
Journal ArticleDOI
Multi-Ethnic Genome-wide Association Study for Atrial Fibrillation
Carolina Roselli,Mark Chaffin,Lu-Chen Weng,Lu-Chen Weng,Stefanie Aeschbacher,Gustav Ahlberg,Christine M. Albert,Peter Almgren,Alvaro Alonso,Christopher D. Anderson,Christopher D. Anderson,Krishna G. Aragam,Krishna G. Aragam,Dan E. Arking,John Barnard,Traci M. Bartz,Emelia J. Benjamin,Emelia J. Benjamin,Nathan A. Bihlmeyer,Joshua C. Bis,Heather L. Bloom,Eric Boerwinkle,Erwin B. Bottinger,Jennifer A. Brody,Hugh Calkins,Archie Campbell,Thomas P. Cappola,John F. Carlquist,John F. Carlquist,Daniel I. Chasman,Daniel I. Chasman,Lin Y. Chen,Yii-Der Ida Chen,Eue Keun Choi,Seung Hoan Choi,Ingrid E. Christophersen,Ingrid E. Christophersen,Ingrid E. Christophersen,Mina K. Chung,John W. Cole,John W. Cole,David Conen,David Conen,James P. Cook,Harry J.G.M. Crijns,Michael J. Cutler,Scott M. Damrauer,Scott M. Damrauer,Brian R. Daniels,Dawood Darbar,Graciela Delgado,Joshua C. Denny,Martin Dichgans,Martin Dichgans,Marcus Dörr,Elton A. M. P. Dudink,Samuel C. Dudley,Nada Esa,Tõnu Esko,Tõnu Esko,Markku Eskola,Diane Fatkin,Diane Fatkin,Diane Fatkin,Stephan B. Felix,Ian Ford,Oscar H. Franco,Bastiaan Geelhoed,Raji P. Grewal,Raji P. Grewal,Vilmundur Gudnason,Xiuqing Guo,Namrata Gupta,Stefan Gustafsson,Rebecca Gutmann,Anders Hamsten,Tamara B. Harris,Caroline Hayward,Susan R. Heckbert,Susan R. Heckbert,Jussi Hernesniemi,Lynne J. Hocking,Albert Hofman,Andrea R. V. R. Horimoto,Jie Huang,Paul L. Huang,Jennifer E. Huffman,Erik Ingelsson,Erik Ingelsson,Esra Gucuk Ipek,Kaoru Ito,Jordi Jimenez-Conde,Jordi Jimenez-Conde,Renee Johnson,J. Wouter Jukema,Stefan Kääb,Mika Kähönen,Yoichiro Kamatani,John P. Kane,Adnan Kastrati,Sekar Kathiresan,Sekar Kathiresan,Petra Katschnig-Winter,Maryam Kavousi,Thorsten Kessler,Bas L.J.H. Kietselaer,Paulus Kirchhof,Marcus E. Kleber,Stacey Knight,Stacey Knight,José Eduardo Krieger,Michiaki Kubo,Lenore J. Launer,Jari Laurikka,Terho Lehtimäki,Kirsten Leineweber,Rozenn N. Lemaitre,Man Li,Man Li,Hong Euy Lim,Henry J. Lin,Honghuang Lin,Honghuang Lin,Lars Lind,Cecilia M. Lindgren,Marja-Liisa Lokki,Barry London,Ruth J. F. Loos,Siew-Kee Low,Yingchang Lu,Leo-Pekka Lyytikäinen,Peter W. Macfarlane,Patrik K. E. Magnusson,Anubha Mahajan,Rainer Malik,Alfredo José Mansur,Gregory M. Marcus,Lauren Margolin,Kenneth B. Margulies,Winfried März,Winfried März,David D. McManus,Olle Melander,Sanghamitra Mohanty,Jay A. Montgomery,Michael Morley,Andrew P. Morris,Martina Müller-Nurasyid,Andrea Natale,Saman Nazarian,Benjamin Neumann,Christopher Newton-Cheh,Christopher Newton-Cheh,Maartje N. Niemeijer,Kjell Nikus,Peter M. Nilsson,Raymond Noordam,Heidi Oellers,Morten S. Olesen,Marju Orho-Melander,Sandosh Padmanabhan,Hui Nam Pak,Guillaume Paré,Guillaume Paré,Nancy L. Pedersen,Joanna Pera,Alexandre C. Pereira,David J. Porteous,Bruce M. Psaty,Bruce M. Psaty,Sara L. Pulit,Sara L. Pulit,Sara L. Pulit,Clive R. Pullinger,Daniel J. Rader,Lena Refsgaard,Marta Ribasés,Marta Ribasés,Paul M. Ridker,Michiel Rienstra,Lorenz Risch,Dan M. Roden,Jonathan Rosand,Jonathan Rosand,Michael A. Rosenberg,Michael A. Rosenberg,Natalia S. Rost,Natalia S. Rost,Jerome I. Rotter,Samir Saba,Roopinder K. Sandhu,Renate B. Schnabel,Katharina Schramm,Heribert Schunkert,Claudia Schurman,Stuart A. Scott,Ilkka Seppälä,Christian M. Shaffer,Svati H. Shah,Alaa Shalaby,Alaa Shalaby,Jaemin Shim,M. Benjamin Shoemaker,Joylene E. Siland,Juha Sinisalo,Moritz F. Sinner,Agnieszka Slowik,Albert V. Smith,Blair H. Smith,J. Gustav Smith,J. Gustav Smith,Jonathan D. Smith,Nicholas L. Smith,Nicholas L. Smith,Elsayed Z. Soliman,Nona Sotoodehnia,Bruno H. Stricker,Albert Y. Sun,Han Sun,Jesper Hastrup Svendsen,Toshihiro Tanaka,Kahraman Tanriverdi,Kent D. Taylor,Maris Teder-Laving,Alexander Teumer,Sébastien Thériault,Sébastien Thériault,Stella Trompet,Nathan R. Tucker,Nathan R. Tucker,Arnljot Tveit,Arnljot Tveit,André G. Uitterlinden,Pim van der Harst,Isabelle C. Van Gelder,David R. Van Wagoner,Niek Verweij,Efthymia Vlachopoulou,Uwe Völker,Biqi Wang,Peter Weeke,Peter Weeke,Bob Weijs,Raul Weiss,Stefan Weiss,Quinn S. Wells,Kerri L. Wiggins,Jorge A. Wong,Daniel Woo,Bradford B. Worrall,Pil Sung Yang,Jie Yao,Zachary T. Yoneda,Tanja Zeller,Lingyao Zeng,Steven A. Lubitz,Steven A. Lubitz,Kathryn L. Lunetta,Kathryn L. Lunetta,Patrick T. Ellinor,Patrick T. Ellinor +260 more
TL;DR: This large, multi-ethnic genome-wide association study identifies 97 loci significantly associated with atrial fibrillation that are enriched for genes involved in cardiac development, electrophysiology, structure and contractile function.