Omid C. Farokhzad

TL;DR: Polydimethylsiloxane substrates with 3D topography at the micrometer and sub‐micrometer levels are developed and used as cell‐culture substrates and show that the physico‐mechanical cues generated by these 3D‐patterned substrates improve the phenotype of the CMs via the reorganization of the cytoskeletal network and the regulation of chromatin conformation.

TL;DR: In this article, self-assembled gel compositions including a gelator, e.g., an enzyme-cleavable gelator having a molecular weight of 2500 or less, are described.

TL;DR: The promoter region of the CD11a gene is cloned and characterized and localized cis-acting elements involved in its expression in lymphoid and myeloid cells are characterized, suggesting that MS-2, a noncovalently associated heterodimeric receptor, may play a major role in regulating myeloids gene expression.

TL;DR: In this paper, the authors provide compositions and systems for delivery of nanocarriers to cells of the immune system, which elicits an immune system response in the form of antibody production, wherein the nanoccarriers lack any T cell antigens.

TL;DR: Intelligent nanotheranostics based on bioresponsive systems have recently emerged and offer the promise of high specificity and efficiency via “on-demand” activation of both therapeutic and diagnostic capabilities.