Omid C. Farokhzad

TL;DR: A comprehensive overview of the interactions between the protein corona and DNA vector, the mechanisms and challenges of nonviral DNA vectors, and important concepts in the design of DNA carriers identified via past reports on DNA delivery systems are provided.

TL;DR: In this article, a synthetic vaccine particle (SVPP) technology was developed to enable co-encapsulation of antigen with potent adjuvants and demonstrated that co-delivery of an antigen with a TLR7/8 or TLR9 agonist in synthetic polymer nanoparticles results in an augmentation of humoral and cellular immune responses with minimal systemic production of inflammatory cytokines.

TL;DR: It is revealed that the decreased superoxide dismutase (SOD) activity by lipid peroxides could be an essential mechanism of the selectively higher ROS generation induced by BP-based nanosheets in cancer cells.

TL;DR: An exfoliation approach is provided that combines calcination, n‐butyllithium exchange and intercalation, and liquid exfoliating processes for the high‐yield synthesis of ultrathin BM NSs that allow for multimodal imaging‐guided breast cancer treatment.

TL;DR: Critical aspects in the area of drug delivery, siRNA, remote-controlled delivery, noninvasive delivery, and nanotechnology in drug delivery are reviewed.