O
Osmo Antikainen
Researcher at University of Helsinki
Publications - 95
Citations - 2446
Osmo Antikainen is an academic researcher from University of Helsinki. The author has contributed to research in topics: Fluid Bed Granulation & Granulation. The author has an hindex of 27, co-authored 94 publications receiving 2234 citations. Previous affiliations of Osmo Antikainen include University of Copenhagen.
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Journal ArticleDOI
Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review
Levente L. Simon,Hajnalka Pataki,György Marosi,Fabian Meemken,Konrad Hungerbühler,Alfons Baiker,Srinivas Tummala,Brian Glennon,Martin Kuentz,Gerry Steele,Herman J. M. Kramer,James W. Rydzak,Zeng-Ping Chen,Julian Morris,Francois Kjell,Ravendra Singh,Rafiqul Gani,Krist V. Gernaey,Marjatta Louhi-Kultanen,John Oreilly,Niklas Sandler,Osmo Antikainen,Jouko Yliruusi,Patrick Frohberg,Joachim Ulrich,Richard D. Braatz,Tom Leyssens,Moritz von Stosch,Rui Oliveira,Reginald B. H. Tan,Huiquan Wu,Mansoor A. Khan,Des O'grady,Anjan Pandey,Remko Westra,Emmanuel Delle-Case,Detlef Pape,Daniele Angelosante,Yannick Maret,Olivier Steiger,Miklos Lenner,Kaoutar Abbou-Oucherif,Zoltan K. Nagy,James D. Litster,Vamsi Krishna Kamaraju,Min-Sen Chiu +45 more
TL;DR: In this paper, a multiauthor review article aims to bring readers up to date with some of the current trends in the field of process analytical technology (PAT) by summarizing each aspect of the subject (sensor development, PAT based process monitoring and control methods) and presenting applications both in industrial laboratories and in manufacture.
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Extrusion-spheronization of pH-sensitive polymeric matrix pellets for possible colonic drug delivery.
Karin Krogars,Jyrki Heinämäki,Johanna Vesalahti,Martti Marvola,Osmo Antikainen,Jouko Yliruusi +5 more
TL;DR: In small amounts Eudragit S increased pellet roundness but in larger amounts pelletroundness was reduced and the combination of citric acid and enteric coating delayed the drug release for 15 min in a pH 7.4 phosphate buffer.
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The effect of compression force on surface structure, crushing strength, friability and disintegration time of erythromycin acistrate tablets
TL;DR: The surface roughness of erythromycin acistrate tablets was studied by non-contact laser profilometry and except for fractal dimension, the roughness parameters behaved very much in the same way as the friability of the tablets.
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Use of the near-infrared reflectance method for measurement of moisture content during granulation.
TL;DR: It is suggested that direct measurement of granule moisture content facilitates the in-process control of the granulation and is applicable for in-line moisture measurement.
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Controlling granule size by granulation liquid feed pulsing.
TL;DR: Granulation liquid feed pulsing is an effective way to modify the particle size of final granules, especially with high inlet air humidity and rapid liquid feed rate processes.