P
Paloma Sánchez-Argüello
Publications - 5
Citations - 242
Paloma Sánchez-Argüello is an academic researcher. The author has contributed to research in topics: Toxicity & Cytotoxicity. The author has an hindex of 4, co-authored 4 publications receiving 219 citations.
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Assessing the effects of fluoxetine on Physa acuta (Gastropoda, Pulmonata) and Chironomus riparius (Insecta, Diptera) using a two-species water-sediment test.
TL;DR: This study showed that fluoxetine can affect reproduction of freshwater molluscs and may contribute to knowledge on ecotoxicology of pharmaceuticals, about which little data is available.
Journal ArticleDOI
Environmental risk assessment for the serotonin re-uptake inhibitor fluoxetine: Case study using the European risk assessment framework.
Ken D. Oakes,Anja Coors,Beate I. Escher,Beate I. Escher,Kathrin Fenner,Jeanne Garric,Marion Gust,Thomas Knacker,Anette Küster,Carola Kussatz,Chris D. Metcalfe,Sara Monteiro,Thomas W. Moon,Jan A. Mennigen,Joanne L. Parrott,Alexandre R.R. Pery,Maria Ramil,Ines Roennefahrt,Jose Tarazona,Paloma Sánchez-Argüello,Thomas A. Ternes,Vance L. Trudeau,Tatiana Boucard,Glen Van Der Kraak,Mark R. Servos +24 more
TL;DR: The serotonin re-uptake inhibitor fluoxetine was selected for an environmental risk assessment, using the most recent European guideline (EMEA 2006), due to its environmental persistence, acute toxicity to nontarget organisms, and unique pharmacokinetics associated with a readily ionizable compound.
Journal ArticleDOI
Linking embryo toxicity with genotoxic responses in the freshwater snail Physa acuta: single exposure to benzo(a)pyrene, fluoxetine, bisphenol A, vinclozolin and exposure to binary mixtures with benzo(a)pyrene.
TL;DR: The results showed that linkage between genotoxicity and embryo toxicity depends on mechanisms of action of compounds under study, and the relative sensitivity of a freshwater mollusc for a range of chemicals was evaluated.
Journal ArticleDOI
Recommendations on the environmental risk assessment of pharmaceuticals: Effect characterization
Heike Schmitt,Tatiana Boucard,Jeanne Garric,John Jensen,Joanne L. Parrott,Alexandre R.R. Pery,Jörg Römbke,Jürg Oliver Straub,Thomas H. Hutchinson,Paloma Sánchez-Argüello,Åke Wennmalm,Karen Duis +11 more
TL;DR: Suggestions for improving the effects testing of pharmaceuticals include inter alia chronic effects testing as a general approach, the use of invertebrate tests including sexual reproduction, the application of endpoints reflecting the mode of action of the drug or known side effects, and the simulation of more realistic exposure conditions in terrestrial laboratory tests.
Journal ArticleDOI
Combined cytotoxicity of ZnO nanoparticles and chlorpyrifos in the rainbow trout, Oncorhynchus mikyss, gonadal cell line RTG-2.
TL;DR: In this article , the in vitro effects of co-exposure of chlorpyrifos (CPF) and ZnO nanoparticles (ZnO NPs) on fish-derived cells were investigated.