P
Paola Francia di Celle
Researcher at University of Turin
Publications - 47
Citations - 1914
Paola Francia di Celle is an academic researcher from University of Turin. The author has contributed to research in topics: Gene rearrangement & Lymphoma. The author has an hindex of 17, co-authored 45 publications receiving 1714 citations. Previous affiliations of Paola Francia di Celle include University of Padua.
Papers
More filters
Journal ArticleDOI
Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies
Andreas Agathangelidis,Nikos Darzentas,Anastasia Hadzidimitriou,Xavier Brochet,Fiona Murray,Xiao-Jie Yan,Zadie Davis,Ellen J. van Gastel-Mol,Cristina Tresoldi,Charles C. Chu,Nicola Cahill,Véronique Giudicelli,Boris Tichy,Lone Bredo Pedersen,Letizia Foroni,Lisa Bonello,Agnieszka Janus,Karin E. Smedby,Achilles Anagnostopoulos,Hélène Merle-Béral,Nikolaos Laoutaris,Gunnar Juliusson,Paola Francia di Celle,Šárka Pospíšilová,Jesper Jurlander,Christian H. Geisler,Athanasios Tsaftaris,Marie-Paule Lefranc,Anton W. Langerak,David Oscier,Nicholas Chiorazzi,Chrysoula Belessi,Frederic Davi,Richard Rosenquist,Paolo Ghia,Kostas Stamatopoulos +35 more
TL;DR: It is documented that CLL may be subdivided into 2 distinct categories: one with stereotyped and the other with nonstereotyped BCRs, at an approximate ratio of 1:2, and evidence suggests a different ontogeny for these 2 categories.
Journal ArticleDOI
Recurrent SETBP1 mutations in atypical chronic myeloid leukemia
Rocco Piazza,Simona Valletta,Nils Winkelmann,Sara Redaelli,Roberta Spinelli,Alessandra Pirola,Laura Antolini,Luca Mologni,Carla Donadoni,Elli Papaemmanuil,Susanne Schnittger,Dong-Wook Kim,Jacqueline Boultwood,Fabio M.V. Rossi,Giuseppe Gaipa,Greta De Martini,Paola Francia di Celle,Hyun Gyung Jang,Hyun Gyung Jang,Valeria Fantin,Valeria Fantin,Graham R. Bignell,Vera Magistroni,Torsten Haferlach,Enrico Maria Pogliani,Peter J. Campbell,Andrew Chase,Andrew Chase,William J. Tapper,William J. Tapper,Nicholas C.P. Cross,Nicholas C.P. Cross,Carlo Gambacorti-Passerini +32 more
TL;DR: Atypical chronic myeloid leukemia (aCML) shares clinical and laboratory features with CML, but it lacks the BCR-ABL1 fusion as mentioned in this paper.
Journal ArticleDOI
FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas
Shanshan Duan,Lukas Cermak,Julia K. Pagan,Mario Rossi,Cinzia Martinengo,Paola Francia di Celle,Bjoern Chapuy,Margaret A. Shipp,Roberto Chiarle,Michele Pagano +9 more
TL;DR: It is shown that BCL6 is targeted for ubiquitylation and proteasomal degradation by a SKP1–CUL1–F-box protein (SCF) ubiquitin ligase complex that contains the orphan F-boxprotein FBXO11, and proposed that mutations and deletions in FBxO11 contribute to lymphomagenesis through BCL 6 stabilization.
Journal ArticleDOI
Simple genetic diagnosis of hairy cell leukemia by sensitive detection of the BRAF-V600E mutation
Enrico Tiacci,Gianluca Schiavoni,Francesco Forconi,Alessia Santi,Livio Trentin,Achille Ambrosetti,Debora Cecchini,Elisa Sozzi,Paola Francia di Celle,Cristiana Di Bello,Alessandro Pulsoni,Robin Foà,Giorgio Inghirami,Brunangelo Falini +13 more
TL;DR: A new, simple, and inexpensive test for genetics-based diagnosis of HCL in whole-blood samples that detects BRAF-V600E through a sensitive allele-specific PCR qualitative assay followed by agarose-gel electrophoresis is described.
Journal Article
Microsatellite instability is associated with the histological features of the tumor in nonfamilial colorectal cancer
Mauro Risio,Gigliola Reato,Paola Francia di Celle,Marco Fizzotti,Francesco Paolo Rossini,Robin Foà +5 more
TL;DR: It is indicated that a link exists between such histological features and somatic genetic instability consistent with a RER(+) phenotype also in nonfamilial colorectal cancer.