Paolo Urbani

TL;DR: These functional CB2 receptors in the brainstem were activated by a CB2 receptor agonist, 2-arachidonoylglycerol, and by elevated endogenous levels of endocannabinoids, which also act at CB1 receptors.

TL;DR: The first potent and specific inhibitors of the biosynthesis of 2-AG that may be used as pharmacological tools to investigate the biological role of this endocannabinoid are reported.

TL;DR: Arvanil does alleviate hyperkinesia typical of HD, although it also affects locomotion in normal rats, and the findings might provide the basis for the development of more specific drugs against HD.

TL;DR: This compound is the first of a novel class of tetraphenyl CB( 1) ligands that, in view of its easy synthesis and high affinity for CB(1) receptors and despite its sterical hindrance, will be useful for the design of new blockers of this therapeutically exploitable receptor type.

TL;DR: The synthesis, antioxidant and antiproliferative activity and a QSAR analysis of synthetic diphenylpropionamide derivatives and their effect on viability of cells and results demonstrated that they are not toxic towards the cell lines used.