P
Patricia A. French
Researcher at Stony Brook University
Publications - 12
Citations - 769
Patricia A. French is an academic researcher from Stony Brook University. The author has contributed to research in topics: Platelet activation & Platelet. The author has an hindex of 8, co-authored 12 publications receiving 698 citations. Previous affiliations of Patricia A. French include Durham University.
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Journal ArticleDOI
Platelet functions beyond hemostasis
Susan S. Smyth,Rodger P. McEver,Andrew S. Weyrich,C. N. Morrell,Maureane Hoffman,Gowthami M. Arepally,Patricia A. French,Harold L. Dauerman,Richard C. Becker +8 more
TL;DR: The process of and factors mediating platelet–platelet and platelet-leukocyte interactions in inflammatory and immune responses are discussed, with the roles of P‐selectin, chemokines and Src family kinases being highlighted.
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G-Protein-Coupled Receptors as Signaling Targets for Antiplatelet Therapy
Susan S. Smyth,Donna S. Woulfe,Jeffrey I. Weitz,Christian Gachet,Pamela B. Conley,Shaun G. Goodman,Matthew T. Roe,Athan Kuliopulos,David J. Moliterno,Patricia A. French,Steven R. Steinhubl,Richard C. Becker +11 more
TL;DR: The identification and development of new agents directed against specific platelet signaling pathways may offer an advantage in preventing thrombotic events while minimizing bleeding risk.
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Platelet Biology and Response to Antiplatelet Therapy in Women: Implications for the Development and Use of Antiplatelet Pharmacotherapies for Cardiovascular Disease
Tracy Y. Wang,Dominick J. Angiolillo,Mary Cushman,Marc S. Sabatine,Paul F. Bray,Susan S. Smyth,Harold L. Dauerman,Patricia A. French,Richard C. Becker +8 more
TL;DR: In this paper, a better understanding of the factors contributing to the observed sex-related differences in platelet biology is warranted, including differences in the frequency and expression of genetic polymorphisms affecting platelet responsiveness to agonists (with and without antiplatelet therapies).
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Genetic regulation of platelet receptor expression and function: application in clinical practice and drug development.
Marlene S. Williams,Ethan J. Weiss,Marc S. Sabatine,Daniel I. Simon,Wadie F. Bahou,Lewis C. Becker,Leslie V. Parise,Harold L. Dauerman,Patricia A. French,Susan S. Smyth,Richard C. Becker +10 more
TL;DR: This article represents an integrated summary of presentations related to genetic regulation of platelet receptor expression and function given at the Fifth Annual Platelet Colloquium in January 2010.
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Bridging the gap between clinical trials of antiplatelet therapies and applications among elderly patients.
Harold L. Dauerman,Deepak L. Bhatt,Deepak L. Bhatt,Daniel D. Gretler,Patricia A. French,Susan S. Smyth,Richard C. Becker +6 more
TL;DR: An increasingly narrow safety index for antiplatelet agents in the elderly and the all-important balance of safety and efficacy--a dynamic continuum that remains paramount in quality of care are underscores.