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Patrick S. G. Chain

Researcher at Los Alamos National Laboratory

Publications -  321
Citations -  38829

Patrick S. G. Chain is an academic researcher from Los Alamos National Laboratory. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 65, co-authored 301 publications receiving 34601 citations. Previous affiliations of Patrick S. G. Chain include McMaster University & Joint Genome Institute.

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Complete Genome Sequence of Yersinia pestis Strains Antiqua and Nepal516: Evidence of Gene Reduction in an Emerging Pathogen

TL;DR: In this paper, the genomes of two isolates of the "classical" antiqua biovar, strains Antiqua and Nepal516, were compared with the corresponding features in Yersinia pseudotuberculosis, and the results showed that grouping Y. pestis strains based strictly on the classical definition of biovars does not accurately reflect the phylogenetic relationships within this species.
Journal Article

Complete Genome Sequence of Yersinia pestis Strains Antiqua and Nepal516: Evidence of Gene Reduction in an Emerging Pathogen

TL;DR: The results presented here clearly demonstrate the differences between the two biovar antiqua lineages and support the notion that grouping Y. pestis strains based strictly on the classical definition of biovars does not accurately reflect the phylogenetic relationships within this species.
Journal ArticleDOI

Whole-Genome-Based Phylogeny and Divergence of the Genus Brucella

TL;DR: A phylogeny using single nucleotide polymorphisms from 13 genomes and rooted the tree using the closely related soil bacterium and opportunistic human pathogen, Ochrobactrum anthropi suggests that most Brucella species diverged from their common B. ovis ancestor in the past 86,000 to 296,000 years, which precedes the domestication of their livestock hosts.