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Paul H. M. Savelkoul
Researcher at Maastricht University
Publications - 253
Citations - 12176
Paul H. M. Savelkoul is an academic researcher from Maastricht University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 52, co-authored 233 publications receiving 10186 citations. Previous affiliations of Paul H. M. Savelkoul include Vanderbilt University Medical Center & University of Amsterdam.
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Journal ArticleDOI
Distribution, origin and contamination risk of coagulase-negative staphylococci from platelet concentrates.
TL;DR: Typing of the CNS strains by AFLP analysis showed that there was not a unique strain which is significantly more often present during bacterial contamination of PCs, and the species identified are mainly recognized as being part of the normal skin flora.
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New Diagnostic Microarray (Check-KPC ESBL) for Detection and Identification of Extended-Spectrum Beta-Lactamases in Highly Resistant Enterobacteriaceae
Ina Willemsen,I. T. M. A. Overdevest,Nashwan al Naiemi,Martine Rijnsburger,Paul H. M. Savelkoul,Christina M. J. E. Vandenbroucke-Grauls,Jan Kluytmans +6 more
TL;DR: The performance of a microarray for the detection of extended-spectrum beta-lactamases was determined on a collection of 638 highly resistant members of the family Enterobacteriaceae collected from patients in 18 hospitals in The Netherlands.
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Applications of real-time PCR in the screening of platelet concentrates for bacterial contamination.
TL;DR: Real-time PCR is an attractive method in development as a more rapid screening test than currently used culture methods to detect bacterial contamination in blood components and may be suitable for generalized bacterial screening of other blood components, such as red blood cells and plasma.
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Monitoring the potential introduction of the Swedish Chlamydia trachomatis variant (swCT) in the Netherlands.
Servaas A. Morré,Arnold Catsburg,Boer, M., de,Joke Spaargaren,Vries, H.J.C., de,J Schirm,Paul H. M. Savelkoul,Steenbergen, J., van,Corien Swaan +8 more
TL;DR: To date the swCT variant has not been found in the Netherlands, however, ongoing monitoring is needed until Roche and Abbott have adapted their CT nucleic acid amplification tests (NAATs) to detect the new variant.
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Immunomodulatory role for membrane vesicles released by THP-1 macrophages and respiratory pathogens during macrophage infection
Charlotte Volgers,Birke J. Benedikter,Gert Grauls,Paul H. M. Savelkoul,Paul H. M. Savelkoul,Frank R. M. Stassen +5 more
TL;DR: Bacterial MVs may play a dual role during infection, as they can both trigger and dampen immune responses thereby contributing to immune defence and bacterial survival.