P
Paul H. M. Savelkoul
Researcher at Maastricht University
Publications - 253
Citations - 12176
Paul H. M. Savelkoul is an academic researcher from Maastricht University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 52, co-authored 233 publications receiving 10186 citations. Previous affiliations of Paul H. M. Savelkoul include Vanderbilt University Medical Center & University of Amsterdam.
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Journal ArticleDOI
Detection and occurrence of plasmid-mediated AmpC in highly resistant gram-negative Rods
E. Ascelijn Reuland,John P. Hays,Denise M. C. de Jongh,Eman Abdelrehim,Ina Willemsen,Jan Kluytmans,Paul H. M. Savelkoul,Christina M. J. E. Vandenbroucke-Grauls,Nashwan al Naiemi +8 more
TL;DR: The disk-based test with cloxacillin showed the best performance as phenotypic confirmation method for AmpC production and the screening for reduced susceptibility to third generation cephalosporins combined with reduced susceptibility with cefoxitin is recommended.
Journal ArticleDOI
Automated Broad-Range Molecular Detection of Bacteria in Clinical Samples
Andries E. Budding,Martine Hoogewerf,Christina M. J. E. Vandenbroucke-Grauls,Paul H. M. Savelkoul +3 more
TL;DR: Investigation of the application of a rapid universal bacterial molecular identification method, IS-pro, to routine patient samples received in a clinical microbiology laboratory indicates that an open molecular approach, such as IS- Pro, may have a high added value for clinical practice.
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Variability of core microbiota in newly diagnosed treatment-naïve paediatric inflammatory bowel disease patients.
T. G. J. de Meij,E. F. J. de Groot,Carel F.W. Peeters,N. K. H. de Boer,C. M. F. Kneepkens,Anat Eck,Marc A. Benninga,Paul H. M. Savelkoul,Paul H. M. Savelkoul,Ad A. van Bodegraven,Andries E. Budding +10 more
TL;DR: Faecal microbiota profiles of children with de novo CD and UC can be discriminated from HC with high accuracy, mainly driven by a decreased abundance of species shaping the microbial core in the healthy state.
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Detection of bacterial DNA in blood samples from febrile patients: underestimated infection or emerging contamination?
Remco P. H. Peters,Tamimount Mohammadi,Christina M. J. E. Vandenbroucke-Grauls,S. A. Danner,Michiel A. van Agtmael,Paul H. M. Savelkoul +5 more
TL;DR: This work applied real-time broad-range polymerase chain reaction (PCR) to detect bacteraemia in blood from febrile patients and found the presence of Burkholderia species DNA while no Burk holderia species grew in culture.
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Characteristics of clinical Helicobacter pylori strains from Ecuador.
Yvette J. Debets-Ossenkopp,Germán Reyes,Janet A. Mulder,Birgit M. aan de Stegge,José T. A. M. Peters,Paul H. M. Savelkoul,Juan Tanca,Amado Salvador Peña,Christina M. J. E. Vandenbroucke-Grauls +8 more
TL;DR: The most prevalent genotype was the cagA(+), vacA s1b,m1 type, which was associated with gastric cancer and peptic ulcer, and Typing by random amplified polymorphic DNA showed no genetic relationship among the strains.